Mouse HIF-1α (Hypoxia Inducible Factor 1 Alpha) CLIA Kit

• Catalog number
  E-CL-M0424-96T
• Price
  Please ask
• Size
  96Test

• Detection Type
  Colormetric
• Target Species
  Mouse
• Target Synonym
  HIF1A, HIF-1A, MOP1, PASD8, bHLHe78, basic helix-loop-helix transcription factor
• Test principle
  This CLIA kit uses the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Mouse HIF-1α . Standards or samples are added to the micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse HIF-1α and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse HIF-1α , biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of Mouse HIF-1α . You can calculate the concentration of Mouse HIF-1α in the samples by comparing the RLU value of the samples to the standard curve.
• Sensitivity
  18.75pg/mL
• Detection Range
  31.25~2000pg/mL
• Target Name
  HIF-1α
• UNIProt ID
  NA
• Tested Sample Types
  Serum, Plasma, Cell supernatant
• Product Name
  Mouse HIF-1α (Hypoxia Inducible Factor 1 Alpha) CLIA Kit
• Type
  Sandwich
• Technical data
• Standard Curve RUL
• Description
  The Mouse HIF-1α (Hypoxia Factor 1 Alpha) CLIA Kit is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  HIF-1α   Hypoxia   Factor   Alpha   CLIA   Kit  
• Gene symbol
  HIF1A, SETD2, ARNT, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1
• Short name
  Mouse HIF-1α (Hypoxia Factor 1 Alpha) CLIA Kit
• Technique
  Mouse, mouses
• Host
  mouse
• Species
  Mouses
• Alternative name
  Mouse HIF-1α (Hypoxia Inducible Factor 1 a) CLIA reagent
• Alternative technique
  murine, kits
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

Gene info

• Identity
  HGNC:4910
• Gene
  HIF1A
• Long gene name
  hypoxia inducible factor 1 subunit alpha
• Synonyms gene name
  • hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
• Synonyms
  • MOP1
  • HIF-1alpha
  • PASD8
  • HIF1
  • bHLHe78
• Synonyms name
  • PAS domain-containing protein 8”, “Class E basic helix-loop-helix protein 78”, “Member of PAS protein 1
• GenBank acession
  • U22431
• Locus
  14q23.2
• Discovery year
  1995-03-27
• Entrez gene record
  3091
• Pubmed identfication
  • 8786149
  • 9079689
• RefSeq identity
  • NM_001530
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000140344

Gene info

• Identity
  HGNC:18420
• Gene
  SETD2
• Long gene name
  SET domain containing 2, histone lysine methyltransferase
• Synonyms gene name
  • SET domain containing 2
• Synonyms
  • HYPB
  • HIF-1
  • KIAA1732
  • FLJ23184
  • KMT3A
• GenBank acession
  • AJ238403
• Locus
  3p21.31
• Discovery year
  2006-02-15
• Entrez gene record
  29072
• Pubmed identfication
  • 16118227
  • 11461154
• RefSeq identity
  • NM_014159
• Classification
  • SET domain containing
  • Lysine methyltransferases
• VEGA ID
  OTTHUMG00000133514
• Locus Specific Databases
  • LRG_775

Gene info

• Identity
  HGNC:700
• Gene
  ARNT
• Long gene name
  aryl hydrocarbon receptor nuclear translocator
• Synonyms
  • HIF-1beta
  • bHLHe2
• GenBank acession
  • AF001307
• Locus
  1q21.3
• Discovery year
  1990-01-22
• Entrez gene record
  405
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000035011

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

Gene info

• Identity
  HGNC:35281
• Gene
  MIR1289-1
• Long gene name
  microRNA 1289-1
• Synonyms gene
  • MIRN1289-1
• Synonyms
  • hsa-mir-1289-1
• Locus
  20q11.22
• Discovery year
  2008-11-03
• Entrez gene record
  100302125
• RefSeq identity
  • NR_031620
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:31488
• Gene
  MIR101-1
• Long gene name
  microRNA 101-1
• Synonyms gene
  • MIRN101-1
• Synonyms
  • hsa-mir-101-1
• Locus
  1p31.3
• Discovery year
  2004-04-23
• Entrez gene record
  406893
• RefSeq identity
  • NR_029516
• Classification
  • MicroRNA MIR101 family

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