Mouse FASL (Factor Related Apoptosis Ligand) CLIA Kit
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Catalog numberE-CL-M0026-96T
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Price:
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Size96Test
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Detection TypeColormetric
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Target SpeciesMouse
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Target SynonymTNFSF6, FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95L
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Test principleThis CLIA kit uses the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Mouse FASL . Standards or samples are added to the micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse FASL and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse FASL , biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of Mouse FASL . You can calculate the concentration of Mouse FASL in the samples by comparing the RLU value of the samples to the standard curve.
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Sensitivity7.5pg/mL
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Detection Range12.5~800pg/mL
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Target NameFASL
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UNIProt IDNA
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Tested Sample TypesSerum, Plasma, Cell supernatant
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Product NameMouse FASL (Factor Related Apoptosis Ligand) CLIA Kit
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TypeSandwich
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DescriptionThis 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
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TestMouseĀ orĀ mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolFASLG
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Short nameMouse FASL (Factor Apoptosis Ligand) CLIA Kit
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Techniqueapoptosis, Mouse, apoptosis pathway, mouses
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Hostmouse
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SpeciesMouse, Mouses
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Alternative nameMouse FASL (Factor Related programmed cellular destruction Ligand) CLIA reagent
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Alternative techniquecelldeath, murine, kits
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Alternative to gene targetv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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Gene info
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Identity
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Gene
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Long gene nameFas ligand
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 6
- Fas ligand (TNF superfamily, member 6)
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-12-09
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
- Death inducing signaling complex
- CD molecules
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VEGA ID
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Locus Specific Databases