Human LOX-1(Lectin Like Oxidized Low Density Lipoprotein Receptor 1) EIA Kit

• Catalog number
  E-EL-H1635-96T
• Price
  Please ask
• Size
  96Test

• Detection Type
  Colormetric
• Target Species
  Human
• Target Synonym
  Oxidized low-density lipoprotein receptor 1,Ox-LDL receptor 1, lectin-type oxidized LDL receptor 1,LOX-1,OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1
• Test principle
  This EIA kit uses the Sandwich-EIA principle. The micro EIA plate provided in this kit has been pre-coated with an antibody specific to Human LOX-1. Standards or samples are added to the micro EIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human LOX-1 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human LOX-1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Human LOX-1. You can calculate the concentration of Human LOX-1 in the samples by comparing the OD of the samples to the standard curve.
• Sensitivity
  0.1ng/mL
• Detection Range
  0.16~10ng/mL
• Target Name
  LOX-1
• UNIProt ID
  P78380
• Tested Sample Types
  Serum, Plasma, Cell supernatant
• Product Name
  Human LOX-1(Lectin Like Oxidized Low Density Lipoprotein Receptor 1) EIA Kit
• Type
  Sandwich
• Technical data
• Standard Curve RUL
• Description
  High and low density proteins are supplied by Elabscience in volumes of 1. Other densities are possible. This ELISA test kit or EIA Enzyme immuno assay is an enzyme linked immuno assay supplied as coated 96 well plates with antigen or antibody and needs to be stored at +4°C. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  MeSH E05 478 566 350 170 Enzyme-Linked Immunosorbent Assay, Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  LOX-1   Lectin   Like   Oxidized   Lipoprotein   Receptor   Kit  
• Gene symbol
  LOX, ALOX15, OLR1, ALOX12B, ALOX5, ALOX12, ALOX15B, ALOXE3, IGHVII-1-1, MIR1-1
• Short name
  LOX-1(Lectin Like Oxidized Lipoprotein Receptor 1) EIA Kit
• Technique
  EIA, eia
• Species
  Human, Humans
• Alternative name
  H. sapiens LOX-1(Lectin Like Oxidized Low Density Lipoprotein Receptor 1) EIA reagent
• Alternative technique
  kits, elisas
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

Gene info

• Identity
  HGNC:6664
• Gene
  LOX
• Long gene name
  lysyl oxidase
• Synonyms name
  • protein-lysine 6-oxidase
• Locus
  5q23.1
• Discovery year
  1986-01-01
• Entrez gene record
  4015
• Pubmed identfication
  • 1685472
• VEGA ID
  OTTHUMG00000128914
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:433
• Gene
  ALOX15
• Long gene name
  arachidonate 15-lipoxygenase
• Synonyms
  • 15-LOX-1
• GenBank acession
  • M23892
• Locus
  17p13.2
• Discovery year
  1992-11-20
• Entrez gene record
  246
• Pubmed identfication
  • 1570320
• Classification
  • Arachidonate lipoxygenases
• VEGA ID
  OTTHUMG00000090746

Gene info

• Identity
  HGNC:8133
• Gene
  OLR1
• Long gene name
  oxidized low density lipoprotein receptor 1
• Synonyms gene name
  • oxidised low density lipoprotein (lectin-like) receptor 1
• Synonyms
  • LOX-1
  • SCARE1
  • CLEC8A
• GenBank acession
  • D89050
• Locus
  12p13.2
• Discovery year
  1998-01-16
• Entrez gene record
  4973
• Pubmed identfication
  • 9763655
• RefSeq identity
  • NM_002543
• Classification
  • C-type lectin domain containing
  • Scavenger receptors
• VEGA ID
  OTTHUMG00000168527

Gene info

• Identity
  HGNC:430
• Gene
  ALOX12B
• Long gene name
  arachidonate 12-lipoxygenase, 12R type
• Synonyms
  • 12R-LOX
• Synonyms name
  • 12R-lipoxygenase
• GenBank acession
  • AF038461
• Locus
  17p13.1
• Discovery year
  1998-07-22
• Entrez gene record
  242
• Pubmed identfication
  • 9618483
• Classification
  • Arachidonate lipoxygenases
• VEGA ID
  OTTHUMG00000108180
• Locus Specific Databases
  • LRG_1264

Gene info

• Identity
  HGNC:435
• Gene
  ALOX5
• Long gene name
  arachidonate 5-lipoxygenase
• Synonyms
  • 5-LOX
• GenBank acession
  • J03571
• Locus
  10q11.21
• Discovery year
  1992-07-10
• Entrez gene record
  240
• Pubmed identfication
  • 2565035
• Classification
  • Arachidonate lipoxygenases
• VEGA ID
  OTTHUMG00000018081

Gene info

• Identity
  HGNC:429
• Gene
  ALOX12
• Long gene name
  arachidonate 12-lipoxygenase, 12S type
• Synonyms gene name
  • arachidonate 12-lipoxygenase
• Synonyms
  • 12S-LOX
• Synonyms name
  • platelet 12-LOX
  • Arachidonate 12-lipoxygenase, 12S-type
• GenBank acession
  • M35418
• Locus
  17p13.1
• Discovery year
  1991-08-07
• Entrez gene record
  239
• Pubmed identfication
  • 1570320
• Classification
  • Arachidonate lipoxygenases
• VEGA ID
  OTTHUMG00000102088

Gene info

• Identity
  HGNC:434
• Gene
  ALOX15B
• Long gene name
  arachidonate 15-lipoxygenase type B
• Synonyms gene name
  • arachidonate 15-lipoxygenase, second type
• Synonyms
  • 15-LOX-2
• GenBank acession
  • U78294
• Locus
  17p13.1
• Discovery year
  1998-07-22
• Entrez gene record
  247
• Pubmed identfication
  • 9177185
• Classification
  • Arachidonate lipoxygenases
• VEGA ID
  OTTHUMG00000108181

Gene info

• Identity
  HGNC:13743
• Gene
  ALOXE3
• Long gene name
  arachidonate lipoxygenase 3
• Synonyms
  • eLOX3
  • E-LOX
• Synonyms name
  • Epidermal lipoxygenase-3
  • hydroperoxide isomerase
• GenBank acession
  • AJ269499
• Locus
  17p13.1
• Discovery year
  2000-11-29
• Entrez gene record
  59344
• Pubmed identfication
  • 12881489
• Classification
  • Arachidonate lipoxygenases
• VEGA ID
  OTTHUMG00000108179

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

MeSH Data

• Name
  Cloning, Molecular
• Concept
  Scope note: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
• Tree numbers
  • E05.393.220
• Qualifiers
  drug effects, methods, radiation effects

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