Rat Suppressor of cytokine signaling 3 (Socs3)

  • Catalog number
    CSB-YP022392RA-200ug
  • Price
    Please ask
  • Size
    200ug
  • Description
    Recombinant Rat Suppressor of cytokine signaling 3(Socs3) expressed in Yeast
  • Specifications
    Uniprot ID: O88583; Host: Rattus norvegicus (Rat); Expression system: Yeast; Expression region: 1-225aa; Sequence information: Full Length; Tag: N-terminal 6xHis-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
  • Additional_information
    MW: 26.8 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
  • Storage_and_shipping
    Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
  • Notes
    For research use only.
  • Additional description
    Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
  • About
    Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
  • Latin name
    Rattus norvegicus
  • Gene target
  • Gene symbol
    SOCS3
  • Short name
    Suppressor of cytokine signaling 3 (Socs3)
  • Host
    Rat
  • Species
    Rat, Rats
  • Alternative name
    Rat Suppressor on cytokine signaling 3 (suppressor on cytokine signaling 3)
  • Alternative to gene target
    suppressor of cytokine signaling 3, ATOD4 and CIS3 and Cish3 and SOCS-3 and SSI-3 and SSI3, SOCS3 and IDBG-70676 and ENSG00000184557 and 9021, protein binding, Cytoplasm, Socs3 and IDBG-214604 and ENSMUSG00000053113 and 12702, SOCS3 and IDBG-647946 and ENSBTAG00000008441 and 282081
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