Rabbit Anti Rat Prnp Antibody-Non-conjugated

• Catalog number
  CSB-PA018739LA01RA_100ug
• Price
  Please ask
• Size
  100ug

• Long name
  Rabbit Antibody against Rat Prnp, Non-conjugated
• Synonym name
  Prnp Rat Antibody
• Species reactivity
  Rat
• Tested applications recommended dilutions
  ELISA
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  P13852
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant rat Major prion protein (29-231AA)
• Immunogen species
  Rat
• Alias
  Major prion protein,PrP,CD230,Prnp,Prn,Prp
• Background
  Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.
• Clonality
  Polyclonal antibody
• Shipping and storage
  Prnp Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Oryctolagus cuniculus, Rattus norvegicus
• French translation
  anticorps

• Gene target
  Prnp   Non-conjugated  
• Short name
  Anti-Prnp
• Technique
  Antibody, Rabbit, anti, antibody to, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Rat, Rats
• Alternative name
  Prnp Antibody
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  prion protein, AltPrP and ASCR and CD230 and CJD and GSS and KURU and p27-30 and PRIP and PrP and PrP27-30 and PrP33-35C and PrPc, PRNP and IDBG-49833 and ENSG00000171867 and 5621, chaperone binding, nuclei, Prnp and IDBG-260830 and ENSMUSG00000079037 and 19122, PRNP and IDBG-639760 and ENSBTAG00000027937 and 281427

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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