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Long name
Rabbit Antibody against Mouse Birc5, Non-conjugated
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Synonym name
Birc5 Mouse Antibody
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Species reactivity
Mouse
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Tested applications recommended dilutions
ELISA
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Conjugation
Non-conjugated
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Antibody isotype
IgG
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UniProt ID
O70201
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Format
Liquid, diluted in buffer
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Buffer composition
Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity
>95%
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Purification method
Protein G purified
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Antibody category
Polyclonal Antibodies
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Immunogen type
Recombinant mouse Baculoviral IAP repeat-containing protein 5 protein (1-140AA)
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Immunogen species
Mouse
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Alias
Apoptosis inhibitor 4,Apoptosis inhibitor survivin,TIAP,Api4, Iap4,Birc5
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Background
Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7.
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Clonality
Polyclonal antibody
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Shipping and storage
Birc5 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. This is against a protein of mus musculus directed antibody.
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Properties
If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus, Oryctolagus cuniculus
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About
Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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French translation
anticorps
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Gene target
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Short name
Anti-Birc5
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Technique
anti mouse, Antibody, Rabbit, Mouse, anti, antibody to, anti mouse antibodies, antibodies against human proteins, antibodies for, antibody Conjugates, mouses
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Host
Rabbit, Rabbits
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Species
Mouse, Mouses
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Alternative name
Birc5 Antibody
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Alternative technique
antibodies, rabbit-anti, murine
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Alternative to gene target
baculoviral IAP repeat containing 5, API4 and EPR-1, BIRC5 and IDBG-70554 and ENSG00000089685 and 332, chaperone binding, nuclei, Birc5 and IDBG-214593 and ENSMUSG00000017716 and 11799, BIRC5 and IDBG-642915 and ENSBTAG00000013573 and 414925
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