Rabbit Anti Human,Rat PSEN2 Antibody-Non-conjugated
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Catalog numberCSB-PA018847LA01HU_50ug
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PricePlease ask
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Size50ug
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Long nameRabbit Antibody against Human, Rat PSEN2, Non-conjugated
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Synonym namePSEN2 Human, Rat Antibody
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Species reactivityHuman,Rat
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Tested applications recommended dilutionsELISA,WB;Recommended dilution:WB:1:500-1:5000
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDP49810
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant Human Presenilin-2 protein (7-77AA)
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Immunogen speciesHuman
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AliasPresenilin-2,PS-2,AD3LP,AD5,E5-1,STM-2,Presenilin-2 NTF subunit,Presenilin-2 CTF subunit,PSEN2,AD4,PS2,PSNL2,STM2
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BackgroundProbable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
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ClonalityPolyclonal antibody
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Shipping and storagePSEN2 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenPresenilin-2
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin nameOryctolagus cuniculus, Rattus norvegicus
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French translationanticorps
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Gene target
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Gene symbolPSEN2
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Short nameAnti-PSEN2
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesRat, Humans, Rats
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Alternative namePSEN2 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetpresenilin 2 (Alzheimer disease 4), AD3L and AD4 and CMD1V and PS2 and STM2, PSEN2 and IDBG-107053 and ENSG00000143801 and 5664, protein binding, nuclei, Psen2 and IDBG-207109 and ENSMUSG00000010609 and 19165, PSEN2 and IDBG-631143 and ENSBTAG00000013197 and 282010
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Gene info
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Identity
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Gene
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Long gene namepresenilin 2
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Synonyms gene
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Synonyms gene name
- Alzheimer disease 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-08-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Peptidase family A22
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data