-
Long name
Rabbit Antibody against Human, Mouse TIRAP, Non-conjugated
-
Synonym name
TIRAP Human, Mouse Antibody
-
Species reactivity
Human,Mouse
-
Tested applications recommended dilutions
ELISA,WB,IHC;Recommended dilution:WB:1:200-1000,IHC:1:20-1:200
-
Conjugation
Non-conjugated
-
Antibody isotype
IgG
-
UniProt ID
P58753
-
Format
Liquid, diluted in buffer
-
Buffer composition
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
Purity
>95%
-
Purification method
Antigen Affinity Purified Antibodies
-
Antibody category
Polyclonal Antibodies
-
Immunogen type
Recombinant human Toll/interleukin-1 receptor domain-containing adapter protein (1-221AA)
-
Immunogen species
Human
-
Alias
TIR domain-containing adapter protein,Adaptor protein Wyatt,MyD88 adapter-like protein,MyD88-2,TIRAP,MAL
-
Background
Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.
-
Clonality
Polyclonal antibody
-
Shipping and storage
TIRAP Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
-
Properties
If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin name
Mus musculus, Oryctolagus cuniculus
-
About
Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
French translation
anticorps
-
Gene target
-
Gene symbol
TIRAP
-
Short name
Anti-TIRAP
-
Technique
anti human, Antibody, Rabbit, Mouse, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates, mouses
-
Host
Rabbit, Rabbits
-
Species
Mouse, Humans, Mouses
-
Alternative name
TIRAP Antibody
-
Alternative technique
antibodies, rabbit-anti, murine
-
Alternative to gene target
toll-interleukin 1 receptor (TIR) domain containing adaptor protein, TIRAP and IDBG-75811 and ENSG00000150455 and 114609, phosphatidylinositol-4, Plasma membranes, Tirap and IDBG-148134 and ENSMUSG00000032041 and 117149, TIRAP and IDBG-642760 and ENSBTAG00000021504 and 531079
-