Rabbit Anti Human XRCC4 Antibody-Non-conjugated

• Catalog number
  CSB-PA614413ESR2HU_100ul
• Price
  Please ask
• Size
  100ul

• Long name
  Rabbit Antibody against Human XRCC4, Non-conjugated
• Synonym name
  XRCC4 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA,IHC;Recommended dilution:IHC:1:20-1:200
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  Q13426
• Format
  Liquid, diluted in buffer
• Buffer composition
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Purity
  >95%
• Purification method
  Antigen Affinity Purified Antibodies
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant human DNA repair protein XRCC4 protein (1-336AA)
• Immunogen species
  Human
• Alias
  X-ray repair cross-complementing protein 4,XRCC4
• Background
  Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
• Clonality
  Polyclonal antibody
• Shipping and storage
  XRCC4 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  XRCC4   Non-conjugated  
• Gene symbol
  XRCC4
• Short name
  Anti-XRCC4
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  XRCC4 Antibody
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  X-ray repair complementing defective repair in Chinese hamster cells 4, XRCC4 and IDBG-32219 and ENSG00000152422 and 7518, protein C-terminus binding, nuclei, Xrcc4 and IDBG-171005 and ENSMUSG00000021615 and 108138, XRCC4 and IDBG-646520 and ENSBTAG00000024275 and 613590

Gene info

• Identity
  HGNC:12831
• Gene
  XRCC4
• Long gene name
  X-ray repair cross complementing 4
• Synonyms gene name
  • X-ray repair complementing defective repair in Chinese hamster cells 4
• Synonyms name
  • X-ray repair, complementing defective, repair in Chinese hamster
  • DNA repair protein XRCC4
• GenBank acession
  • AB017445
• Locus
  5q14.2
• Discovery year
  1990-10-16
• Entrez gene record
  7518
• Pubmed identfication
  • 1697445
  • 7665175
• RefSeq identity
  • NM_022550
• VEGA ID
  OTTHUMG00000131319

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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