Rabbit Anti Human WDR34 Antibody-Non-conjugated
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Catalog numberCSB-PA842668LA01HU_100ug
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PricePlease ask
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Size100ug
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Long nameRabbit Antibody against Human WDR34, Non-conjugated
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Synonym nameWDR34 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,WB,IHC;Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ96EX3
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human WD repeat-containing protein 34 protein (1-210AA)
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Immunogen speciesHuman
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AliasWD repeat-containing protein 34,WDR34
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BackgroundCritical for ciliary functions, essential to normal development and survival, most probably as a previously unrecognized component of the mammalian dynein-motor-based intraflagellar transport (IFT) machinery. Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation.
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ClonalityPolyclonal antibody
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Shipping and storageWDR34 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolDYNC2I2
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Short nameAnti-WDR34
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameWDR34 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Gene info
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Identity
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Gene
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Long gene namedynein 2 intermediate chain 2
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Synonyms gene
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Synonyms gene name
- WD repeat domain 34
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-02-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Dynein 2 complex subunits
- WD repeat domain containing
- Cilia and flagella associated
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data