Rabbit Anti Human VPS39 Antibody-Biotin

• Catalog number
  CSB-PA836235LD01HU_100ug
• Price
  Please ask
• Size
  100ug

• Long name
  Rabbit Antibody against Human VPS39, Biotin
• Synonym name
  VPS39 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA
• Conjugation
  Biotin
• Antibody isotype
  IgG
• UniProt ID
  Q96JC1
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant Human Vam6/Vps39-like protein (263-490AA)
• Immunogen species
  Human
• Alias
  Vam6/Vps39-like protein,TRAP1-like protein,hVam6p,VPS39,KIAA0770,TLP,VAM6
• Background
  Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription. Does not affect TGF-beta-induced SMAD2 or SMAD3 phosphorylation, nor SMAD2/SMAD4 complex formation.
• Clonality
  Polyclonal antibody
• Shipping and storage
  VPS39 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Short name of the antigen
  Vam6/Vps39-like protein
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional conjugation
  Biotinylated
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  VPS39  
• Gene symbol
  VPS39-DT, VPS39
• Short name
  Anti-VPS39
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
• Host
  Rabbit, Rabbits
• Label
  Biotin
• Species
  Human, Humans
• Alternative name
  VPS39 Antibody,Biotin conjugated
• Alternative technique
  antibodies, rabbit-anti

Gene info

• Identity
  HGNC:55378
• Gene
  VPS39-DT
• Long gene name
  VPS39 divergent transcript
• Locus
  15q15.1
• Discovery year
  2020-11-12
• Entrez gene record
  105370795
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:20593
• Gene
  VPS39
• Long gene name
  VPS39 subunit of HOPS complex
• Synonyms gene name
  • vacuolar protein sorting 39 (yeast)
  • vacuolar protein sorting 39 homolog (S. cerevisiae)
  • VPS39, HOPS complex subunit
• Synonyms
  • KIAA0770
  • VAM6
• GenBank acession
  • AF280814
• Locus
  15q15.1
• Discovery year
  2003-09-04
• Entrez gene record
  23339
• Pubmed identfication
  • 11448994
  • 26463206
• RefSeq identity
  • NM_015289
• Classification
  • HOPS complex
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000130467

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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