Rabbit Anti Human UBA1 Antibody-HRP
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Catalog numberCSB-PA00149B0Rb_100ug
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PricePlease ask
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Size100ug
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Long nameRabbit Antibody against Human UBA1, HRP
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Synonym nameUBA1 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA
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ConjugationHRP
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Antibody isotypeIgG
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UniProt IDP22314
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant Human Ubiquitin-like modifier-activating enzyme 1 protein (730-881AA)
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Immunogen speciesHuman
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AliasUbiquitin-like modifier-activating enzyme 1,Protein A1S9,Ubiquitin-activating enzyme E1,UBA1,A1S9T,UBE1
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BackgroundCatalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system (PubMed:1606621, PubMed:1447181). Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP (PubMed:1447181). Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (PubMed:22456334).
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ClonalityPolyclonal antibody
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Shipping and storageUBA1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenUbiquitin-like modifier-activating enzyme 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional conjugationHRP Conjugated
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolUBA1
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Short nameAnti-UBA1
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
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HostRabbit, Rabbits
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LabelHRP
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SpeciesHuman, Humans
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Alternative nameUBA1 Antibody,HRP conjugated
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Alternative techniqueantibodies, rabbit-anti
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Gene info
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Identity
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Gene
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Long gene nameubiquitin like modifier activating enzyme 1
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Synonyms gene
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Synonyms gene name
- ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing)
- ubiquitin-activating enzyme E1
- ubiquitin-like modifier activating enzyme 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-07-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Cilia and flagella associated
- Ubiquitin like modifier activating enzymes
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data