Rabbit Anti Human TRPM2 Antibody-Non-conjugated
-
Catalog numberCSB-PA025084ESR1HU_50ul
-
PricePlease ask
-
Size50ul
-
-
Long nameRabbit Antibody against Human TRPM2, Non-conjugated
-
Synonym nameTRPM2 Human Antibody
-
Species reactivityHuman
-
Tested applications recommended dilutionsELISA,IHC;Recommended dilution:IHC:1:20-1:200
-
ConjugationNon-conjugated
-
Antibody isotypeIgG
-
UniProt IDO94759
-
FormatLiquid, diluted in buffer
-
Buffer compositionPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
Purity>95%
-
Purification methodAntigen Affinity Purified Antibodies
-
Antibody categoryPolyclonal Antibodies
-
Immunogen typeRecombinant human Transient receptor potential cation channel subfamily M member 2 protein (1204-1503AA)
-
Immunogen speciesHuman
-
AliasEstrogen-responsive element-associated gene 1 protein,Long transient receptor potential channel 2,LTrpC-2,LTrpC2,Transient receptor potential channel 7,TRPM2,EREG1, KNP3, LTRPC2, TRPC7
-
BackgroundNonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD+), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.
-
ClonalityPolyclonal antibody
-
Shipping and storageTRPM2 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
-
PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin nameOryctolagus cuniculus
-
French translationanticorps
-
Gene target
-
Gene symbolTRPM2-AS, TRPM2
-
Short nameAnti-TRPM2
-
Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
-
HostRabbit, Rabbits
-
SpeciesHuman, Humans
-
Alternative nameTRPM2 Antibody
-
Alternative techniqueantibodies, rabbit-anti
-
Gene info
-
Identity
-
Gene
-
Long gene nameTRPM2 antisense RNA
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2014-06-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Antisense RNAs
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nametransient receptor potential cation channel subfamily M member 2
-
Synonyms gene
-
Synonyms gene name
- transient receptor potential cation channel, subfamily M, member 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1998-03-23
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Transient receptor potential cation channels
- Nudix hydrolase family
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data