Rabbit Anti Human TRADD Antibody-Non-conjugated
-
Catalog numberCSB-PA621879ESR2HU_50ul
-
PricePlease ask
-
Size50ul
-
-
Long nameRabbit Antibody against Human TRADD, Non-conjugated
-
Synonym nameTRADD Human Antibody
-
Species reactivityHuman
-
Tested applications recommended dilutionsELISA,WB,IHC;Recommended dilution:WB:1:500-2000,IHC:1:20-1:200
-
ConjugationNon-conjugated
-
Antibody isotypeIgG
-
UniProt IDQ15628
-
FormatLiquid, diluted in buffer
-
Buffer compositionPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
Purity>95%
-
Purification methodAntigen Affinity Purified Antibodies
-
Antibody categoryPolyclonal Antibodies
-
Immunogen typeRecombinant human Tumor necrosis factor receptor type 1-associated DEATH domain protein (1-312AA)
-
Immunogen speciesHuman
-
AliasTNFR1-associated DEATH domain protein,TNFRSF1A-associated via death domain,TRADD
-
BackgroundThe nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
-
ClonalityPolyclonal antibody
-
Shipping and storageTRADD Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
-
PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin nameOryctolagus cuniculus
-
French translationanticorps
-
Gene target
-
Gene symbolTRADD
-
Short nameAnti-TRADD
-
Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
-
HostRabbit, Rabbits
-
SpeciesHuman, Humans
-
Alternative nameTRADD Antibody
-
Alternative techniqueantibodies, rabbit-anti
-
Alternative to gene targetTNFRSF1A-associated via death domain, Hs.89862, TRADD and IDBG-36010 and ENSG00000102871 and 8717, binding, nuclei, Tradd and IDBG-186918 and ENSMUSG00000031887 and 71609, TRADD and IDBG-633302 and ENSBTAG00000012642 and 504707
-
Gene info
-
Identity
-
Gene
-
Long gene nameTNFRSF1A associated via death domain
-
Synonyms gene name
- TNFRSF1A-associated via death domain
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-05-07
-
Entrez gene record
-
Pubmed identfication
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data