Rabbit Anti Human SNAI1 Antibody-Non-conjugated
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Catalog numberCSB-PA021867LA01HU_50ug
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PricePlease ask
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Size50ug
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Long nameRabbit Antibody against Human SNAI1, Non-conjugated
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Synonym nameSNAI1 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,IHC;Recommended dilution:IHC:1:20-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDO95863
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human Zinc finger protein SNAI1 protein (1-264AA)
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Immunogen speciesHuman
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AliasZinc finger protein SNAI1,SNAI1,SNAH,Protein snail homolog 1,Protein sna
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BackgroundInvolved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.
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ClonalityPolyclonal antibody
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Shipping and storageSNAI1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolSNAI1
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Short nameAnti-SNAI1
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameSNAI1 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetsnail homolog 1 (Drosophila), dJ710H13.1 and SLUGH2 and SNA and SNAH and SNAIL and SNAIL1, SNAI1 and IDBG-80676 and ENSG00000124216 and 6615, metal ion binding, nuclei, Snai1 and IDBG-213071 and ENSMUSG00000042821 and 20613, BT.61987 and IDBG-643208 and ENSBTAG00000014554 and 504492
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Gene info
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Identity
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Gene
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Long gene namesnail family transcriptional repressor 1
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Synonyms gene name
- snail 1 (drosophila homolog), zinc finger protein
- snail homolog 1 (Drosophila)
- snail family zinc finger 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-07-03
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Entrez gene record
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Pubmed identfication
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Classification
- Zinc fingers C2H2-type
- SNAG transcriptional repressors
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data