Rabbit Anti Human SIN3A Antibody-Non-conjugated
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Catalog numberCSB-PA836303LA01HU_100ug
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PricePlease ask
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Size100ug
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Long nameRabbit Antibody against Human SIN3A, Non-conjugated
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Synonym nameSIN3A Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,WB,IHC;Recommended dilution:WB:1:500-1:5000,IHC:1:20-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ96ST3
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant Human Paired amphipathic helix protein Sin3a protein (1-123AA)
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Immunogen speciesHuman
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AliasPaired amphipathic helix protein Sin3a,Histone deacetylase complex subunit Sin3a,Transcriptional corepressor Sin3a,SIN3A
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BackgroundActs as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression (By similarity).
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ClonalityPolyclonal antibody
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Shipping and storageSIN3A Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenPaired amphipathic helix protein Sin3a
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolSIN3A
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Short nameAnti-SIN3A
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameSIN3A Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetSIN3 transcription regulator homolog A (yeast), SIN3A and IDBG-23397 and ENSG00000169375 and 25942, protein deacetylase activity, nuclei, Sin3a and IDBG-169269 and ENSMUSG00000042557 and 20466, SIN3A and IDBG-631394 and ENSBTAG00000009985 and 518504
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Gene info
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Identity
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Gene
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Long gene nameSIN3 transcription regulator family member A
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Synonyms gene name
- SIN3 homolog A, transcription regulator (yeast)
- SIN3 transcription regulator homolog A (yeast)
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-10-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EMSY complex
- SIN3 histone deacetylase complex subunits
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data