Rabbit Anti Human RRM2B Antibody-Non-conjugated
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Catalog numberCSB-PA745339ESR1HU_100ul
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PricePlease ask
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Size100ul
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Long nameRabbit Antibody against Human RRM2B, Non-conjugated
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Synonym nameRRM2B Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,WB,IHC,IP;Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ7LG56
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FormatLiquid, diluted in buffer
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Buffer compositionPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Purity>95%
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Purification methodAntigen Affinity Purified Antibodies
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human Ribonucleoside-diphosphate reductase subunit M2 B protein (1-351AA)
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Immunogen speciesHuman
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AliasTP53-inducible ribonucleotide reductase M2 B,p53-inducible ribonucleotide reductase small subunit 2-like protein, p53R2,RRM2B,P53R2
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BackgroundPlays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
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ClonalityPolyclonal antibody
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Shipping and storageRRM2B Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolRRM2B
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Short nameAnti-RRM2B
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameRRM2B Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetribonucleotide reductase M2 B (TP53 inducible), RRM2B and IDBG-31119 and ENSG00000048392 and 50484, ribonucleoside-diphosphate reductase activity, nuclei, Rrm2b and IDBG-135832 and ENSMUSG00000022292 and 382985, RRM2B and IDBG-645071 and ENSBTAG00000021208 and 528960
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Gene info
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Identity
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Gene
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Long gene nameribonucleotide reductase regulatory TP53 inducible subunit M2B
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Synonyms gene name
- ribonucleotide reductase M2 B (TP53 inducible)
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-01-14
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Entrez gene record
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Pubmed identfication
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data