Rabbit Anti Human RRM2B Antibody-Non-conjugated

  • Catalog number
    CSB-PA745339ESR1HU_100ul
  • Price
    Please ask
  • Size
    100ul
  • Long name
    Rabbit Antibody against Human RRM2B, Non-conjugated
  • Synonym name
    RRM2B Human Antibody
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA,WB,IHC,IP;Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000
  • Conjugation
    Non-conjugated
  • Antibody isotype
    IgG
  • UniProt ID
    Q7LG56
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Purity
    >95%
  • Purification method
    Antigen Affinity Purified Antibodies
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant human Ribonucleoside-diphosphate reductase subunit M2 B protein (1-351AA)
  • Immunogen species
    Human
  • Alias
    TP53-inducible ribonucleotide reductase M2 B,p53-inducible ribonucleotide reductase small subunit 2-like protein, p53R2,RRM2B,P53R2
  • Background
    Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    RRM2B Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
  • Properties
    If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • About
    Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
  • Latin name
    Oryctolagus cuniculus
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    RRM2B
  • Short name
    Anti-RRM2B
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
  • Host
    Rabbit, Rabbits
  • Species
    Human, Humans
  • Alternative name
    RRM2B Antibody
  • Alternative technique
    antibodies, rabbit-anti
  • Alternative to gene target
    ribonucleotide reductase M2 B (TP53 inducible), RRM2B and IDBG-31119 and ENSG00000048392 and 50484, ribonucleoside-diphosphate reductase activity, nuclei, Rrm2b and IDBG-135832 and ENSMUSG00000022292 and 382985, RRM2B and IDBG-645071 and ENSBTAG00000021208 and 528960
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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