Rabbit Anti Human, Rat LILRB1 Antibody-Non-conjugated
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Catalog numberCSB-PA847747LA01HU_100ug
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PricePlease ask
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Size100ug
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Long nameRabbit Antibody against Human, Rat LILRB1, Non-conjugated
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Synonym nameLILRB1 Human, Rat Antibody
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Species reactivityHuman, Rat
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Tested applications recommended dilutionsELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ8NHL6
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 1 protein (483-650AA)
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Immunogen speciesHuman
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AliasLeukocyte immunoglobulin-like receptor subfamily B member 1, LIR-1, Leukocyte immunoglobulin-like receptor 1, CD85 antigen-like family member J, Immunoglobulin-like transcript 2, ILT-2, Monocyte/macrophage immunoglobulin-like receptor 7, MIR-7, CD85j, LILRB1, ILT2, LIR1, MIR7
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BackgroundReceptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
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ClonalityPolyclonal antibody
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Shipping and storageLILRB1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenLeukocyte immunoglobulin-like receptor subfamily B member 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin nameOryctolagus cuniculus, Rattus norvegicus
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French translationanticorps
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Gene target
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Gene symbolLILRB1-AS1, LILRB1
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Short nameAnti-LILRB1
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesRat, Humans, Rats
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Alternative nameLILRB1 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetleukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1, CD85J and ILT-2 and ILT2 and LIR-1 and LIR1 and MIR-7 and MIR7, LILRB1 and IDBG-68880 and ENSG00000104972 and 10859, protein homodimerization activity, Cell surfaces
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Gene info
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Identity
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Gene
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Long gene nameLILRB1 antisense RNA 1
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Synonyms
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Locus
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Discovery year2017-02-10
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Pubmed identfication
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene nameleukocyte immunoglobulin like receptor B1
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Synonyms gene name
- leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-01-11
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Entrez gene record
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Pubmed identfication
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Classification
- CD molecules
- Inhibitory leukocyte immunoglobulin like receptors
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data