Rabbit Anti Human, Rat ITGB6 Antibody-Non-conjugated

• Catalog number
  CSB-PA011890LA01HU_50ug
• Price
  Please ask
• Size
  50ug

• Long name
  Rabbit Antibody against Human, Rat ITGB6, Non-conjugated
• Synonym name
  ITGB6 Human, Rat Antibody
• Species reactivity
  Human, Rat
• Tested applications recommended dilutions
  ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  P18564
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant Human Integrin beta-6 protein (451-586AA)
• Immunogen species
  Human
• Alias
  Integrin beta-6, ITGB6
• Background
  Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:17158881).
• Clonality
  Polyclonal antibody
• Shipping and storage
  ITGB6 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Short name of the antigen
  Integrin beta-6
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Oryctolagus cuniculus, Rattus norvegicus
• French translation
  anticorps

• Gene target
  ITGB6   Non-conjugated  
• Gene symbol
  ITGB6
• Short name
  Anti-ITGB6
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Rat, Humans, Rats
• Alternative name
  ITGB6 Antibody
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  integrin, beta 6, ITGB6 and IDBG-73389 and ENSG00000115221 and 100505984,3694, integrin binding, Cell surfaces, Itgb6 and IDBG-173466 and ENSMUSG00000026971 and 16420, ITGB6 and IDBG-641392 and ENSBTAG00000009080 and 282644

Gene info

• Identity
  HGNC:6161
• Gene
  ITGB6
• Long gene name
  integrin subunit beta 6
• Synonyms gene name
  • integrin, beta 6
• Locus
  2q24.2
• Discovery year
  1992-02-14
• Entrez gene record
  3694
• Pubmed identfication
  • 1729173
  • 8120056
• RefSeq identity
  • NM_000888
• Classification
  • Integrin beta subunits
• VEGA ID
  OTTHUMG00000132026

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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