Rabbit Anti Human PDK1 Antibody-HRP
-
Catalog numberCSB-PA613584LB01HU_100ug
-
PricePlease ask
-
Size100ug
-
-
Long nameRabbit Antibody against Human PDK1, HRP
-
Synonym namePDK1 Human Antibody
-
Species reactivityHuman
-
Tested applications recommended dilutionsELISA
-
ConjugationHRP
-
Antibody isotypeIgG
-
UniProt IDQ15118
-
FormatLiquid, diluted in buffer
-
Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
-
Purity>95%
-
Purification methodProtein G purified
-
Antibody categoryPolyclonal Antibodies
-
Immunogen typeRecombinant Human [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial protein (294-432AA)
-
Immunogen speciesHuman
-
Alias[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,mitochondrial ,Pyruvate dehydrogenase kinase isoform 1,PDH kinase 1,PDK1,PDHK1
-
BackgroundKinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.
-
ClonalityPolyclonal antibody
-
Shipping and storagePDK1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
-
Short name of the antigen[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
-
PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Additional conjugationHRP Conjugated
-
AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin nameOryctolagus cuniculus
-
French translationanticorps
-
Gene target
-
Gene symbolPDK1, PDPK1
-
Short nameAnti-PDK1
-
Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
-
HostRabbit, Rabbits
-
LabelHRP
-
SpeciesHuman, Humans
-
Alternative namePDK1 Antibody,HRP conjugated
-
Alternative techniqueantibodies, rabbit-anti
-
Gene info
-
Identity
-
Gene
-
Long gene namepyruvate dehydrogenase kinase 1
-
Synonyms gene name
- pyruvate dehydrogenase kinase, isoenzyme 1
- pyruvate dehydrogenase kinase, isozyme 1
-
GenBank acession
-
Locus
-
Discovery year1996-08-14
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name3-phosphoinositide dependent protein kinase 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1998-03-23
-
Entrez gene record
-
Pubmed identfication
-
Classification
- AGC family kinases
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data