Rabbit Anti Human PAN2 Antibody-FITC
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Catalog numberCSB-PA681391LC01HU_50ug
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PricePlease ask
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Size50ug
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Long nameRabbit Antibody against Human PAN2, FITC
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Synonym namePAN2 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA
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ConjugationFITC
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Antibody isotypeIgG
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UniProt IDQ504Q3
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human PAB-dependent poly(A)-specific ribonuclease subunit PAN2 protein (628-908AA)
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Immunogen speciesHuman
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AliasPAB-dependent poly(A)-specific ribonuclease subunit PAN2UniRule annotation,Inactive ubiquitin carboxyl-terminal hydrolase 52,PAN2
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BackgroundCatalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
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ClonalityPolyclonal antibody
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Shipping and storagePAN2 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenPAB-dependent poly(A)-specific ribonuclease subunit PAN2
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Cusabio Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Cusabio FITC is highly sensitive to pH extremes. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional conjugationAnti-FITC Antibody
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolRDH14, PAN2, NLRP4
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Short nameAnti-PAN2
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Techniqueanti human, Antibody, Rabbit, anti, FITC, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, Fluorescein
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HostRabbit, Rabbits
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LabelFITC
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SpeciesHuman, Humans
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Alternative namePAN2 Antibody,FITC conjugated
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Alternative techniqueantibodies, rabbit-anti, fluorescine
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Gene info
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Identity
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Gene
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Long gene nameretinol dehydrogenase 14
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Synonyms gene name
- retinol dehydrogenase 14 (all-trans and 9-cis)
- retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-12-11
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Entrez gene record
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Pubmed identfication
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Classification
- Short chain dehydrogenase/reductase superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namepoly(A) specific ribonuclease subunit PAN2
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Synonyms gene
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Synonyms gene name
- ubiquitin specific protease 52
- ubiquitin specific peptidase 52
- PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
- PAN2 poly(A) specific ribonuclease subunit
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-09-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- WD repeat domain containing
- Ubiquitin specific peptidases
- Exonucleases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNLR family pyrin domain containing 4
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Synonyms gene
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Synonyms gene name
- NACHT, leucine rich repeat and PYD containing 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-10-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NLR family
- Pyrin domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
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Tree numbers
- E01.370.225.500.607.512.240
- E01.370.225.750.551.512.240
- E05.200.500.607.512.240
- E05.200.750.551.512.240
- E05.478.583.375
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data