Rabbit Anti Human NOD2 Antibody-Non-conjugated
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Catalog numberCSB-PA881021LA01HU_50ug
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PricePlease ask
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Size50ug
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Long nameRabbit Antibody against Human NOD2, Non-conjugated
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Synonym nameNOD2 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,IHC,IF;Recommended dilution:IHC:1:20-1:200,IF:1:50-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ9HC29
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant Human Nucleotide-binding oligomerization domain-containing protein 2 protein (460-733AA)
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Immunogen speciesHuman
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AliasNucleotide-binding oligomerization domain-containing protein 2,Caspase recruitment domain-containing protein 15,Inflammatory bowel disease protein 1,NOD2,CARD15,IBD1
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BackgroundInvolved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages (PubMed:18511561).
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ClonalityPolyclonal antibody
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Shipping and storageNOD2 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenNucleotide-binding oligomerization domain-containing protein 2
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolNOD2
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Short nameAnti-NOD2
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameNOD2 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetnucleotide-binding oli this GO merization domain containing 2, NOD2 and IDBG-30654 and ENSG00000167207 and 64127, CARD domain binding, Cell surfaces, Nod2 and IDBG-179050 and ENSMUSG00000055994 and 257632, NOD2 and IDBG-631640 and ENSBTAG00000020936 and 444867
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Gene info
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Identity
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Gene
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Long gene namenucleotide binding oligomerization domain containing 2
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Synonyms gene
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Synonyms gene name
- caspase recruitment domain family, member 15
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-07-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NLR family
- Caspase recruitment domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data