Rabbit Anti Human MMP2 Antibody-Non-conjugated

• Catalog number
  CSB-PA06879A0Rb_100ug
• Price
  Please ask
• Size
  100ug

• Long name
  Rabbit Antibody against Human MMP2, Non-conjugated
• Synonym name
  MMP2 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA,IHC,IF;Recommended dilution:IHC:1:20-1:200,IF:1:50-1:200
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  P08253
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant human 72 kDa type IV collagenase protein (445-660AA)
• Immunogen species
  Human
• Alias
  72 kDa type IV collagenase,72 kDa gelatinase,Gelatinase A,Matrix metalloproteinase-2,MMP-2,TBE-1,MMP2,CLG4A
• Background
  Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14.
• Clonality
  Polyclonal antibody
• Shipping and storage
  MMP2 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  MMP2   Non-conjugated  
• Gene symbol
  MMP2-AS1, MMP2
• Short name
  Anti-MMP2
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  MMP2 Antibody
• Alternative technique
  antibodies, rabbit-anti

Gene info

• Identity
  HGNC:53142
• Gene
  MMP2-AS1
• Long gene name
  MMP2 antisense RNA 1
• Synonyms
  • ENST00000569037
• Locus
  16q12.2
• Discovery year
  2017-02-16
• Entrez gene record
  107984884
• Pubmed identfication
  • 27816668
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:7166
• Gene
  MMP2
• Long gene name
  matrix metallopeptidase 2
• Synonyms gene
  • CLG4
  • CLG4A
• Synonyms gene name
  • matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
• Synonyms
  • TBE-1
• Locus
  16q12.2
• Discovery year
  1989-05-25
• Entrez gene record
  4313
• Classification
  • M10 matrix metallopeptidases
• VEGA ID
  OTTHUMG00000133202

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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