Rabbit Anti Human MET Antibody-FITC

• Catalog number
  CSB-PA013714LC01HU_100ug
• Price
  Please ask
• Size
  100ug

• Long name
  Rabbit Antibody against Human MET, FITC
• Synonym name
  MET Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA
• Conjugation
  FITC
• Antibody isotype
  IgG
• UniProt ID
  P08581
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant Human Hepatocyte growth factor receptor protein (83-209AA)
• Immunogen species
  Human
• Alias
  Hepatocyte growth factor receptor,HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met,MET
• Background
  Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells. May regulate cortical bone osteogenesis (By similarity).
• Clonality
  Polyclonal antibody
• Shipping and storage
  MET Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Short name of the antigen
  Hepatocyte growth factor receptor
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Cusabio Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Cusabio FITC is highly sensitive to pH extremes. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional conjugation
  Anti-FITC Antibody
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  MET  
• Gene symbol
  SLTM, MET, TRM-CAT4-3, TRM-CAT5-1, TRM-CAT3-2, TRM-CAT7-1, TRM-CAT5-2, TRM-CAT2-1, TRM-CAT3-1, TRM-CAT4-2
• Short name
  Anti-MET
• Technique
  anti human, Antibody, Rabbit, anti, FITC, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, Fluorescein
• Host
  Rabbit, Rabbits
• Label
  FITC
• Species
  Human, Humans
• Alternative name
  MET Antibody,FITC conjugated
• Alternative technique
  antibodies, rabbit-anti, fluorescine

Gene info

• Identity
  HGNC:20709
• Gene
  SLTM
• Long gene name
  SAFB like transcription modulator
• Synonyms
  • Met
  • FLJ13213
• GenBank acession
  • BC046119
• Locus
  15q22.1
• Discovery year
  2005-11-08
• Entrez gene record
  79811
• RefSeq identity
  • NM_024755
• Classification
  • RNA binding motif containing
• VEGA ID
  OTTHUMG00000074033

Gene info

• Identity
  HGNC:7029
• Gene
  MET
• Long gene name
  MET proto-oncogene, receptor tyrosine kinase
• Synonyms gene name
  • met proto-oncogene
• Synonyms
  • HGFR
  • RCCP2
  • DFNB97
• Synonyms name
  • hepatocyte growth factor receptor
• GenBank acession
  • M35073
• Locus
  7q31
• Discovery year
  1986-01-01
• Pubmed identfication
  • 1846706
  • 1611909
  • 25941349
• Classification
  • Receptor tyrosine kinases
  • IPT domain containing
• VEGA ID
  OTTHUMG00000023299
• Locus Specific Databases
  • LRG_662

Gene info

• Identity
  HGNC:34959
• Gene
  TRM-CAT4-3
• Long gene name
  tRNA-Met (anticodon CAT) 4-3
• Synonyms gene
  • TRNAM20
• Synonyms gene name
  • transfer RNA methionine 20 (anticodon CAU)
  • transfer RNA-Met (CAT) 4-3
• Synonyms
  • tRNA-Met-CAT-4-3
• GenBank acession
  • HG983956
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  107986682
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34869
• Gene
  TRM-CAT5-1
• Long gene name
  tRNA-Met (anticodon CAT) 5-1
• Synonyms gene
  • TRNAM16
• Synonyms gene name
  • transfer RNA methionine 16 (anticodon CAU)
  • transfer RNA-Met (CAT) 5-1
• Synonyms
  • tRNA-Met-CAT-5-1
• GenBank acession
  • HG983957
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189303
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34673
• Gene
  TRM-CAT3-2
• Long gene name
  tRNA-Met (anticodon CAT) 3-2
• Synonyms gene
  • TRNAM8
• Synonyms gene name
  • transfer RNA methionine 8 (anticodon CAU)
  • transfer RNA-Met (CAT) 3-2
• Synonyms
  • tRNA-Met-CAT-3-2
• GenBank acession
  • HG983953
• Locus
  6p22.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189111
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34645
• Gene
  TRM-CAT7-1
• Long gene name
  tRNA-Met (anticodon CAT) 7-1
• Synonyms gene
  • TRNAM5
• Synonyms gene name
  • transfer RNA methionine 5 (anticodon CAU)
  • transfer RNA-Met (CAT) 7-1
• Synonyms
  • tRNA-Met-CAT-7-1
• GenBank acession
  • HG983959
• Locus
  6p11.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189085
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:54713
• Gene
  TRM-CAT5-2
• Long gene name
  tRNA-Met (anticodon CAT) 5-2
• Synonyms
  • tRNA-Met-CAT-5-2
• Locus
  6p22.2
• Discovery year
  2019-12-06
• Entrez gene record
  107986680
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34697
• Gene
  TRM-CAT2-1
• Long gene name
  tRNA-Met (anticodon CAT) 2-1
• Synonyms gene
  • TRNAM9
• Synonyms gene name
  • transfer RNA methionine 9 (anticodon CAU)
  • transfer RNA-Met (CAT) 2-1
• Synonyms
  • tRNA-Met-CAT-2-1
• GenBank acession
  • HG983951
• Locus
  16q22.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189135
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34779
• Gene
  TRM-CAT3-1
• Long gene name
  tRNA-Met (anticodon CAT) 3-1
• Synonyms gene
  • TRNAM12
• Synonyms gene name
  • transfer RNA methionine 12 (anticodon CAU)
  • transfer RNA-Met (CAT) 3-1
• Synonyms
  • tRNA-Met-CAT-3-1
• GenBank acession
  • HG983952
• Locus
  6p22.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189216
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34922
• Gene
  TRM-CAT4-2
• Long gene name
  tRNA-Met (anticodon CAT) 4-2
• Synonyms gene
  • TRNAM19
• Synonyms gene name
  • transfer RNA methionine 19 (anticodon CAU)
  • transfer RNA-Met (CAT) 4-2
• Synonyms
  • tRNA-Met-CAT-4-2
• GenBank acession
  • HG983955
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189354
• Classification
  • Cytoplasmic transfer RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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