Rabbit Anti Human MED1 Antibody-Non-conjugated
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Catalog numberCSB-PA621880HA01HU_100ug
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PricePlease ask
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Size100ug
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Long nameRabbit Antibody against Human MED1, Non-conjugated
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Synonym nameMED1 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,IHC;Recommended dilution:IHC:1:20-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ15648
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human Mediator of RNA polymerase II transcription subunit 1 protein (878-1031AA)
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Immunogen speciesHuman
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AliasMediator of RNA polymerase II transcription subunit 1,Activator-recruited cofactor 205 kDa component,ARC205,Mediator complex subunit 1,Peroxisome proliferator-activated,MED1,ARC205,CRSP1,CRSP200,DRIP205,DRIP230,PBP,PPARBP,PPARGBP,RB18A,TRAP220,TRIP2
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BackgroundComponent of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (PubMed:10406464, PubMed:11867769, PubMed:12037571, PubMed:12218053, PubMed:12556447, PubMed:14636573, PubMed:15340084, PubMed:15471764, PubMed:15989967, PubMed:16574658, PubMed:9653119). Acts as a coactivator for GATA1-mediated transcriptional activation during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781).
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ClonalityPolyclonal antibody
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Shipping and storageMED1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenMediator of RNA polymerase II transcription subunit 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolMBD4, MED1
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Short nameAnti-MED1
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameMED1 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetmediator complex subunit 1, CRSP1 and CRSP200 and DRIP205 and DRIP230 and PBP and PPARBP and PPARGBP and RB18A and TRAP220 and TRIP2, MED1 and IDBG-45623 and ENSG00000125686 and 5469, LBD domain binding, nuclei, Med1 and IDBG-210500 and ENSMUSG00000018160 and 19014, MED1 and IDBG-639352 and ENSBTAG00000013236 and 520734
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Gene info
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Identity
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Gene
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Long gene namemethyl-CpG binding domain 4, DNA glycosylase
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Synonyms gene name
- methyl-CpG binding domain protein 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-01-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- DNA glycosylases
- Methyl-CpG binding domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemediator complex subunit 1
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Synonyms gene
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Synonyms gene name
- PPAR binding protein
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mediator complex
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data