Rabbit Anti Human LRP4 Antibody-Non-conjugated
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Catalog numberCSB-PA013099ESR2HU_100ul
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PricePlease ask
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Size100ul
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Long nameRabbit Antibody against Human LRP4, Non-conjugated
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Synonym nameLRP4 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,IHC;Recommended dilution:IHC:1:20-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDO75096
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FormatLiquid, diluted in buffer
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Buffer compositionPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Purity>95%
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Purification methodAntigen Affinity Purified Antibodies
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human Low-density lipoprotein receptor-related protein 4 protein (1500-1725AA)
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Immunogen speciesHuman
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AliasLow-density lipoprotein receptor-related protein 4,LRP-4,Multiple epidermal growth factor-like domains 7,LRP4,KIAA0816,LRP10,MEGF7
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BackgroundMediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Alternatively, may be involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway. More generally, has been proposed to function as a cell surface endocytic receptor binding and internalizing extracellular ligands for degradation by lysosomes.
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ClonalityPolyclonal antibody
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Shipping and storageLRP4 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenLow-density lipoprotein receptor-related protein 4
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolLRP4-AS1, LRP4, CORIN
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Short nameAnti-LRP4
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameLRP4 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetlow density lipoprotein receptor-related protein 4, CLSS and LRP-4 and LRP10 and MEGF7 and SOST2, LRP4 and IDBG-42508 and ENSG00000134569 and 4038, scaffold protein binding, Cell surfaces, Lrp4 and IDBG-191212 and ENSMUSG00000027253 and 228357, BT.103632 and IDBG-637271 and ENSBTAG00000008429 and 504317
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Gene info
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Identity
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Gene
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Long gene nameLRP4 antisense RNA 1
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Synonyms gene name
- LRP4 antisense RNA 1 (non-protein coding)
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Locus
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Discovery year2012-06-23
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Entrez gene record
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameLDL receptor related protein 4
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Synonyms gene name
- low density lipoprotein receptor-related protein 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-03-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Low density lipoprotein receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecorin, serine peptidase
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Synonyms gene name
- corin, serine protease
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-05-10
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Entrez gene record
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Pubmed identfication
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Classification
- Scavenger receptor cysteine rich domain containing
- Type II transmembrane serine proteases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
