Rabbit Anti Human KLF1 Antibody-Non-conjugated

  • Catalog number
    CSB-PA619760LA01HU_50ug
  • Price
    Please ask
  • Size
    50ug
  • Long name
    Rabbit Antibody against Human KLF1, Non-conjugated
  • Synonym name
    KLF1 Human Antibody
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA
  • Conjugation
    Non-conjugated
  • Antibody isotype
    IgG
  • UniProt ID
    Q13351
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant human Krueppel-like factor 1 protein (1-362AA)
  • Immunogen species
    Human
  • Alias
    Krueppel-like factor 1,Erythroid krueppel-like transcription factor,EKLF,KLF1,EKLF
  • Background
    Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    KLF1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
  • Properties
    If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • About
    Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
  • Latin name
    Oryctolagus cuniculus
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    KLF1
  • Short name
    Anti-KLF1
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
  • Host
    Rabbit, Rabbits
  • Species
    Human, Humans
  • Alternative name
    KLF1 Antibody
  • Alternative technique
    antibodies, rabbit-anti
  • Alternative to gene target
    Kruppel-like factor 1 (erythroid), CDAN4 and EKLF and HBFQTL6 and INLU, KLF1 and IDBG-31252 and ENSG00000105610 and 10661, metal ion binding, nuclei, Klf1 and IDBG-175231 and ENSMUSG00000054191 and 16596, KLF1 and IDBG-642908 and ENSBTAG00000006083 and 784295
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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