Rabbit Anti Human KLF1 Antibody-Non-conjugated
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Catalog numberCSB-PA619760LA01HU_50ug
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PricePlease ask
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Size50ug
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Long nameRabbit Antibody against Human KLF1, Non-conjugated
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Synonym nameKLF1 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ13351
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human Krueppel-like factor 1 protein (1-362AA)
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Immunogen speciesHuman
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AliasKrueppel-like factor 1,Erythroid krueppel-like transcription factor,EKLF,KLF1,EKLF
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BackgroundTranscription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.
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ClonalityPolyclonal antibody
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Shipping and storageKLF1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolKLF1
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Short nameAnti-KLF1
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameKLF1 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetKruppel-like factor 1 (erythroid), CDAN4 and EKLF and HBFQTL6 and INLU, KLF1 and IDBG-31252 and ENSG00000105610 and 10661, metal ion binding, nuclei, Klf1 and IDBG-175231 and ENSMUSG00000054191 and 16596, KLF1 and IDBG-642908 and ENSBTAG00000006083 and 784295
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Gene info
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Identity
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Gene
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Long gene nameKruppel like factor 1
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Synonyms gene name
- Kruppel-like factor 1 (erythroid)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-12-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Kruppel like factors
- Zinc fingers C2H2-type
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data