Rabbit Anti Human IL36RN Antibody-Non-conjugated
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Catalog numberCSB-PA866201DSR1HU_100ul
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PricePlease ask
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Size100ul
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Long nameRabbit Antibody against Human IL36RN, Non-conjugated
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Synonym nameIL36RN Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,IHC;Recommended dilution:IHC:1:20-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ9UBH0
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FormatLiquid, diluted in buffer
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Buffer compositionPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Purity>95%
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Purification methodAntigen Affinity Purified Antibodies
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human Interleukin-36 receptor antagonist protein (1-155AA)
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Immunogen speciesHuman
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AliasIL-36Ra,FIL1 delta,IL-1-related protein 3,IL-1RP3,Interleukin-1 HY1,IL-1HY1,Interleukin-1 delta,IL-1 delta,Interleukin-1 family member 5,IL-1F5,Interleukin-1 receptor antagonist homolog 1,IL-1ra homolog 1,Interleukin-1-like protein 1,IL-1L1,IL36RN,FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3
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BackgroundInhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.
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ClonalityPolyclonal antibody
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Shipping and storageIL36RN Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolIL36RN
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Short nameAnti-IL36RN
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameIL36RN Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetinterleukin 36 receptor anta this GO nist, IL36RN and IDBG-66761 and ENSG00000136695 and 26525, interleukin-1 receptor anta this GO nist activity, Extracellular, Il1f5 and IDBG-142281 and ENSMUSG00000026983 and 54450, BT.56045 and IDBG-634660 and ENSBTAG00000039839 and 518514
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Gene info
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Identity
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Gene
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Long gene nameinterleukin 36 receptor antagonist
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 5 (delta)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data