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Long name
Rabbit Antibody against Human GZMB, HRP
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Synonym name
GZMB Human Antibody
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Species reactivity
Human
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Tested applications recommended dilutions
ELISA
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Conjugation
HRP
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Antibody isotype
IgG
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UniProt ID
P10144
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Format
Liquid, diluted in buffer
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Buffer composition
Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity
>95%
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Purification method
Protein G purified
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Antibody category
Polyclonal Antibodies
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Immunogen type
Recombinant human Granzyme B protein (21-247AA)
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Immunogen species
Human
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Alias
C11,CTLA-1,Cathepsin G-like 1,CTSGL1,Cytotoxic T-lymphocyte proteinase 2,Lymphocyte protease,Fragmentin-2,Granzyme-2,Human lymphocyte protein,HLP,SECT,T-cell serine protease 1-3E,GZMB,CGL1, CSPB, CTLA1, GRB
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Background
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
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Clonality
Polyclonal antibody
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Shipping and storage
GZMB Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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Properties
If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional conjugation
HRP Conjugated
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About
Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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French translation
anticorps
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Gene target
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Gene symbol
GZMB
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Short name
Anti-GZMB
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Technique
anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
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Host
Rabbit, Rabbits
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Label
HRP
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Species
Human, Humans
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Alternative name
GZMB Antibody,HRP conjugated
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Alternative technique
antibodies, rabbit-anti
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Alternative to gene target
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), CCPI and CGL-1 and CGL1 and CSP-B and CSPB and CTLA1 and CTSGL1 and HLP and SECT, GZMB and IDBG-4054 and ENSG00000100453 and 3002, serine-type peptidase activity, nuclei, BT.19365 and IDBG-632083 and ENSBTAG00000010057 and 508646
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