Rabbit Anti Human GREM1 Antibody-Non-conjugated

• Catalog number
  CSB-PA009892LA01HU_100ug
• Price
  Please ask
• Size
  100ug

• Long name
  Rabbit Antibody against Human GREM1, Non-conjugated
• Synonym name
  GREM1 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA, IHC; Recommended dilution: IHC:1:200-1:500
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  O60565
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant Human Gremlin-1 protein (18-184AA)
• Immunogen species
  Human
• Alias
  Gremlin-1, Cell proliferation-inducing gene 2 protein, Cysteine knot superfamily 1, BMP antagonist 1, DAN domain family member 2, Down-regulated in Mos-transformed cells protein, Increased in high glucose protein 21, GREM1, CKTSF1B1, DAND2, DRM, PIG2
• Background
  Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (PubMed:27036124). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed (By similarity).
• Clonality
  Polyclonal antibody
• Shipping and storage
  GREM1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Short name of the antigen
  Gremlin-1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  GREM1   Non-conjugated  
• Gene symbol
  GREM1-AS1, GREM1
• Short name
  Anti-GREM1
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  GREM1 Antibody
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  gremlin 1, GREM1 and IDBG-5193 and ENSG00000166923 and 26585, receptor a this GO nist activity, Extracellular, Grem1 and IDBG-197200 and ENSMUSG00000074934 and 23892, GREM1 and IDBG-648566 and ENSBTAG00000046604 and 539079

Gene info

• Identity
  HGNC:55411
• Gene
  GREM1-AS1
• Long gene name
  GREM1 antisense RNA 1
• Locus
  15q13.3
• Discovery year
  2021-01-06
• Entrez gene record
  100131315
• RefSeq identity
  • NR_109767
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:2001
• Gene
  GREM1
• Long gene name
  gremlin 1, DAN family BMP antagonist
• Synonyms gene
  • CKTSF1B1
  • CRAC1
• Synonyms gene name
  • cysteine knot superfamily 1, BMP antagonist 1
  • gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)
  • gremlin 1
  • colorectal adenoma and carcinoma 1
• Synonyms
  • DRM
  • gremlin
  • DAND2
  • HMPS
• Synonyms name
  • hereditary mixed polyposis syndrome
  • down-regulated in mos-transformed cells
• Locus
  15q13.3
• Discovery year
  1999-12-02
• Entrez gene record
  26585
• Pubmed identfication
  • 9660951
  • 10026205
  • 22561515
  • 27385727
• RefSeq identity
  • NM_013372
• Classification
  • DAN family
• VEGA ID
  OTTHUMG00000129319
• Locus Specific Databases
  • LRG_1365

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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