Rabbit Anti Human GLRX2 Antibody-Non-conjugated

• Catalog number
  CSB-PA878876DSR1HU_100ul
• Price
  Please ask
• Size
  100ul

• Long name
  Rabbit Antibody against Human GLRX2, Non-conjugated
• Synonym name
  GLRX2 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA,IHC;Recommended dilution:IHC:1:20-1:200
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  Q9NS18
• Format
  Liquid, diluted in buffer
• Buffer composition
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Purity
  >95%
• Purification method
  Antigen Affinity Purified Antibodies
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant human Glutaredoxin-2, mitochondrial protein (1-124AA)
• Immunogen species
  Human
• Alias
  GLRX2,GRX2,CGI-133
• Background
  Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
• Clonality
  Polyclonal antibody
• Shipping and storage
  GLRX2 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  GLRX2   Non-conjugated  
• Gene symbol
  GLRX2
• Short name
  Anti-GLRX2
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  GLRX2 Antibody
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  glutaredoxin 2, GLRX2 and IDBG-105482 and ENSG00000023572 and 51022, 2 iron, nuclei, Glrx2 and IDBG-196991 and ENSMUSG00000018196 and 69367, GLRX2 and IDBG-629600 and ENSBTAG00000015972 and 513762

Gene info

• Identity
  HGNC:16065
• Gene
  GLRX2
• Long gene name
  glutaredoxin 2
• Synonyms gene name
  • glutaredoxin (thioltransferase) 2
• Synonyms
  • GRX2
  • bA101E13.1
• GenBank acession
  • AF132495
• Locus
  1q31.2
• Discovery year
  2001-08-24
• Entrez gene record
  51022
• Pubmed identfication
  • 11297543
• RefSeq identity
  • NM_016066
• Classification
  • Glutaredoxin domain containing
• VEGA ID
  OTTHUMG00000035677

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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