Rabbit Anti Human GDF5 Antibody-Non-conjugated

• Catalog number
  CSB-PA009349ESR1HU_50ul
• Price
  Please ask
• Size
  50ul

• Long name
  Rabbit Antibody against Human GDF5, Non-conjugated
• Synonym name
  GDF5 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA,IHC;Recommended dilution:IHC:1:20-1:200
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  P43026
• Format
  Liquid, diluted in buffer
• Buffer composition
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Purity
  >95%
• Purification method
  Antigen Affinity Purified Antibodies
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant human Growth/differentiation factor 5 protein (202-501AA)
• Immunogen species
  Human
• Alias
  Growth/differentiation factor 5,GDF-5,Bone morphogenetic protein 14,BMP-14,Cartilage-derived morphogenetic protein 1,CDMP-1,Lipopolysaccharide-associated protein 4,LAP-4,LPS-associated protein 4,GDF5,BMP14, CDMP1
• Background
  Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 (By similarity). Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.
• Clonality
  Polyclonal antibody
• Shipping and storage
  GDF5 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  GDF5   Non-conjugated  
• Gene symbol
  GDF5, GDF5-AS1
• Short name
  Anti-GDF5
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  GDF5 Antibody
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  growth differentiation factor 5, BDA1C and BMP-14 and BMP14 and CDMP1 and LAP-4 and LAP4 and OS5 and SYM1B and SYNS2, GDF5 and IDBG-70038 and ENSG00000125965 and 8200, growth factor activity, Extracellular, Gdf5 and IDBG-210734 and ENSMUSG00000038259 and 14563, BT.86382 and IDBG-642165 and ENSBTAG00000004429 and 539559

Gene info

• Identity
  HGNC:4220
• Gene
  GDF5
• Long gene name
  growth differentiation factor 5
• Synonyms
  • CDMP1
  • BMP14
• Synonyms name
  • cartilage-derived morphogenetic protein-1
• GenBank acession
  • X80915
• Locus
  20q11.22
• Discovery year
  1997-12-05
• Entrez gene record
  8200
• Pubmed identfication
  • 9288091
  • 9288098
• Classification
  • Transforming growth factor beta superfamily
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000032341

Gene info

• Identity
  HGNC:33435
• Gene
  GDF5-AS1
• Long gene name
  GDF5 antisense RNA 1
• Synonyms gene
  • GDF5OS
• Synonyms gene name
  • growth differentiation factor 5 opposite strand
• GenBank acession
  • BC085019
• Locus
  20q11.22
• Discovery year
  2007-04-12
• Entrez gene record
  554250
• RefSeq identity
  • NR_161326
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000055985

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products