Rabbit Anti Human DOCK7 Antibody-Non-conjugated

• Catalog number
  CSB-PA836266LA01HU_50ug
• Price
  Please ask
• Size
  50ug

• Long name
  Rabbit Antibody against Human DOCK7, Non-conjugated
• Synonym name
  DOCK7 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA,WB,IF;Recommended dilution:WB:1:2000-1:5000,IF:1:50-1:200
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  Q96N67
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
• Immunogen species
  Human
• Alias
  Dedicator of cytokinesis protein 7,DOCK7,KIAA1771
• Background
  Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
• Clonality
  Polyclonal antibody
• Shipping and storage
  DOCK7 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Short name of the antigen
  Dedicator of cytokinesis protein 7
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  DOCK7   Non-conjugated  
• Gene symbol
  DOCK7-DT, DOCK7
• Short name
  Anti-DOCK7
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  DOCK7 Antibody
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  dedicator of cytokinesis 7, DOCK7 and IDBG-99358 and ENSG00000116641 and 85440, Rac GTPase binding, multiple, Dock7 and IDBG-165723 and ENSMUSG00000028556 and 67299, DOCK7 and IDBG-638579 and ENSBTAG00000019877 and 537464

Gene info

• Identity
  HGNC:55670
• Gene
  DOCK7-DT
• Long gene name
  DOCK7 divergent transcript
• Locus
  1p31.3
• Discovery year
  2021-06-30
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:19190
• Gene
  DOCK7
• Long gene name
  dedicator of cytokinesis 7
• Synonyms
  • KIAA1771
  • ZIR2
• Locus
  1p31.3
• Discovery year
  2003-11-19
• Entrez gene record
  85440
• Pubmed identfication
  • 12432077
• RefSeq identity
  • NM_033407
• Classification
  • DOCK family Rho GEFs
• VEGA ID
  OTTHUMG00000013131

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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