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Long name
Rabbit Antibody against Human DIO2, Non-conjugated
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Synonym name
DIO2 Human Antibody
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Species reactivity
Human
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Tested applications recommended dilutions
ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200
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Conjugation
Non-conjugated
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Antibody isotype
IgG
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UniProt ID
Q92813
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Format
Liquid, diluted in buffer
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Buffer composition
Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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Purity
>95%
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Purification method
Protein G purified
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Antibody category
Polyclonal Antibodies
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Immunogen type
Recombinant Human Type II iodothyronine deiodinase protein (74-222AA)
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Immunogen species
Human
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Alias
Type II iodothyronine deiodinase, 5DII, DIOII, Type 2 DI, Type-II 5'-deiodinase, DIO2, ITDI2, TXDI2
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Background
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
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Clonality
Polyclonal antibody
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Shipping and storage
DIO2 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigen
Type II iodothyronine deiodinase
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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Properties
If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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French translation
anticorps
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Gene target
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Gene symbol
DIO2-AS1, DIO2
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Short name
Anti-DIO2
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Technique
anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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Host
Rabbit, Rabbits
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Species
Human, Humans
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Alternative name
DIO2 Antibody
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Alternative technique
antibodies, rabbit-anti
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Alternative to gene target
deiodinase, iodothyronine, type II, 5DII and D2 and DIOII and SelY and TXDI2, DIO2 and IDBG-14346 and ENSG00000211448 and 1734, ubiquitin protein ligase binding, Plasma membranes, Dio2 and IDBG-161130 and ENSMUSG00000007682 and 13371, DIO2 and IDBG-646906 and ENSBTAG00000001605 and 494548
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