Rabbit Anti Human CFLAR Antibody-Biotin
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Catalog numberCSB-PA005282LD01HU_100ug
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PricePlease ask
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Size100ug
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Long nameRabbit Antibody against Human CFLAR, Biotin
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Synonym nameCFLAR Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA
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ConjugationBiotin
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Antibody isotypeIgG
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UniProt IDO15519
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human CASP8 and FADD-like apoptosis regulator protein (1-250AA)
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Immunogen speciesHuman
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AliasCASP8 and FADD-like apoptosis regulator,CFLAR,CASH,CASP8AP1,CLARP,MRIT,Caspase homolog,CASH,Caspase-eight-related protein,Casper,Caspase-like apoptosis regulatory protein,CLARP,Cellular FLICE-like inhibitory protein,c-FLIP,FADD-like antiapoptotic molecule 1,FLAME-1,Inhibitor of FLICE,I-FLICE,MACH-related inducer of toxicity,MRIT,Usurpin,CASP8 and FADD-like apoptosis regulator subunit p43,CASP8 and FADD-like apoptosis regulator subunit p12
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BackgroundApoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
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ClonalityPolyclonal antibody
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Shipping and storageCFLAR Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional conjugationBiotinylated
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolCFLAR-AS1, CFLAR
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Short nameAnti-CFLAR
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
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HostRabbit, Rabbits
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LabelBiotin
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SpeciesHuman, Humans
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Alternative nameCFLAR Antibody,Biotin conjugated
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetCASP8 and FADD-like apoptosis regulator, c-FLIP and c-FLIPL and c-FLIPR and c-FLIPS and CASH and CASP8AP1 and Casper and CLARP and FLAME and FLAME-1 and FLAME1 and FLIP and I-FLICE and MRIT, CFLAR and IDBG-78386 and ENSG00000003402 and 8837, death effector domain binding, Plasma membranes, FLIP and IDBG-643202 and ENSBTAG00000010998 and 497199
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Gene info
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Identity
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Gene
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Long gene nameCFLAR antisense RNA 1
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Synonyms gene
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Synonyms gene name
- amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 10
- CFLAR antisense RNA 1 (non-protein coding)
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GenBank acession
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Locus
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Discovery year2001-01-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCASP8 and FADD like apoptosis regulator
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Synonyms gene
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Synonyms gene name
- CASP8 and FADD-like apoptosis regulator
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-05-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
- Death effector domain containing
- Death inducing signaling complex
- Ripoptosome
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
