Rabbit Anti Human CCM2 Antibody-Non-conjugated
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Catalog numberCSB-PA866275ESR2HU_50ul
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PricePlease ask
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Size50ul
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Long nameRabbit Antibody against Human CCM2, Non-conjugated
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Synonym nameCCM2 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,IHC;Recommended dilution:IHC:1:20-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ9BSQ5
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FormatLiquid, diluted in buffer
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Buffer compositionPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Purity>95%
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Purification methodAntigen Affinity Purified Antibodies
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human Cerebral cavernous malformations 2 protein (1-300AA)
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Immunogen speciesHuman
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AliasCerebral cavernous malformations 2 protein,Malcavernin,CCM2,C7orf22,PP10187
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BackgroundComponent of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity).
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ClonalityPolyclonal antibody
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Shipping and storageCCM2 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenCerebral cavernous malformations 2 protein
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolCCM2
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Short nameAnti-CCM2
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameCCM2 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetcerebral cavernous malformation 2, CCM2 and IDBG-15466 and ENSG00000136280 and 83605, protein binding, Cytoplasm, Ccm2 and IDBG-148293 and ENSMUSG00000000378 and 216527, CCM2 and IDBG-634072 and ENSBTAG00000008090 and 506450
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Gene info
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Identity
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Gene
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Long gene nameCCM2 scaffold protein
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Synonyms gene
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Synonyms gene name
- chromosome 7 open reading frame 22
- cerebral cavernous malformation 2
- CCM2 scaffolding protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-07-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CCM adhesion complex
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data