Rabbit Anti Human BACE1 Antibody-Non-conjugated

• Catalog number
  CSB-PA002524LA01HU_100ug
• Price
  Please ask
• Size
  100ug

• Long name
  Rabbit Antibody against Human BACE1, Non-conjugated
• Synonym name
  BACE1 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA,IHC,IF;Recommended dilution:IHC:1:20-1:200,IF:1:50-1:200
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  P56817
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant Human Beta-secretase 1 protein (46-155AA)
• Immunogen species
  Human
• Alias
  Beta-secretase 1,Aspartyl protease 2,ASP2,Asp 2,Beta-site amyloid precursor protein cleaving enzyme 1,Beta-site APP cleaving enzyme 1,Memapsin-2,Membrane-associated aspartic protease 2,BACE1,BACE,KIAA1149
• Background
  Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
• Clonality
  Polyclonal antibody
• Shipping and storage
  BACE1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Short name of the antigen
  Beta-secretase 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  BACE1   Non-conjugated  
• Gene symbol
  BACE1, BACE1-AS
• Short name
  Anti-BACE1
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  BACE1 Antibody
• Alternative technique
  antibodies, rabbit-anti

Gene info

• Identity
  HGNC:933
• Gene
  BACE1
• Long gene name
  beta-secretase 1
• Synonyms gene
  • BACE
• Synonyms gene name
  • beta-site APP-cleaving enzyme
  • beta-site APP-cleaving enzyme 1
• GenBank acession
  • AF190725
• Locus
  11q23.3
• Discovery year
  1999-10-29
• Entrez gene record
  23621
• Pubmed identfication
  • 10531052
• Classification
  • Peptidase family A1
• VEGA ID
  OTTHUMG00000160636

Gene info

• Identity
  HGNC:37125
• Gene
  BACE1-AS
• Long gene name
  BACE1 antisense RNA
• Synonyms gene
  • BACE1AS
• Synonyms gene name
  • BACE1 antisense RNA (non-protein coding)
• Synonyms
  • FJ573250
  • NCRNA00177
  • BACE1-AS1
• Synonyms name
  • non-protein coding RNA 177
• Locus
  11q23.3
• Discovery year
  2009-07-15
• Entrez gene record
  100379571
• Pubmed identfication
  • 18587408
  • 21785702
• RefSeq identity
  • NR_037803
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000188154

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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