Rabbit Anti Epstein-Barr virus LMP2 Antibody-HRP
-
Catalog numberCSB-PA321086HB01EFA_50ug
-
PricePlease ask
-
Size50ug
-
-
Long nameRabbit Antibody against Epstein-Barr virus LMP2, HRP
-
Synonym nameLMP2 Epstein-Barr virus Antibody
-
Species reactivityEpstein-Barr virus
-
Tested applications recommended dilutionsELISA
-
ConjugationHRP
-
Antibody isotypeIgG
-
UniProt IDP13285
-
FormatLiquid, diluted in buffer
-
Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
-
Purity>95%
-
Purification methodProtein G purified
-
Antibody categoryPolyclonal Antibodies
-
Immunogen typeRecombinant Epstein-Barr virus Latent membrane protein 2 protein (1-147AA)
-
Immunogen speciesEpstein-Barr virus
-
AliasLatent membrane protein 2,Terminal protein,LMP2
-
BackgroundIsoform LMP2A maintains EBV latent infection of B-lymphocyte, by preventing lytic reactivation of the virus in response to surface immunoglobulin (sIg) cross-linking. Acts like a dominant negative inhibitor of the sIg-associated protein tyrosine kinases, LYN and SYK. Also blocks translocation of the B-cell antigen receptor (BCR) into lipid rafts, preventing the subsequent signaling and accelerated internalization of the BCR upon BCR cross-linking. Serves as a molecular scaffold to recruit SYK, LYN and E3 protein-ubiquitin ligases, such as ITCH and NEDD4L, leading to ubiquitination and potential degradation of both tyrosines kinases. Possesses a constitutive signaling activity in non-transformed cells, inducing bypass of normal B lymphocyte developmental checkpoints allowing immunoglobulin-negative cells to colonize peripheral lymphoid organs.
-
ClonalityPolyclonal antibody
-
Shipping and storageLMP2 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
-
Short name of the antigenLatent membrane protein 2
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
-
PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
-
Additional conjugationHRP Conjugated
-
AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin nameOryctolagus cuniculus
-
French translationanticorps
-
Gene target
-
Gene symbolPSMB9
-
Short nameAnti-LMP2
-
TechniqueAntibody, Rabbit, anti, antibody to, antibodies against human proteins, antibodies for
-
HostRabbit, Rabbits
-
LabelHRP
-
SpeciesVirus, Viruses
-
Alternative nameLMP2 Antibody,HRP conjugated
-
Alternative techniqueantibodies, rabbit-anti
-
Virusepstein
-
Gene info
-
Identity
-
Gene
-
Long gene nameproteasome 20S subunit beta 9
-
Synonyms gene
-
Synonyms gene name
- proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2)
- large multifunctional peptidase 2
- proteasome (prosome, macropain) subunit, beta type, 9
- proteasome subunit beta 9
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1991-12-18
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Proteasome
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data