Mouse Tumor necrosis factor (Tnf)

• Catalog number
  CSB-EP023955MO1-500ug
• Price
  Please ask
• Size
  500ug

• Description
  Recombinant Mouse Tumor necrosis factor(Tnf),partial expressed in E.coli
• Specifications
  Uniprot ID: P06804; Host: Mus musculus (Mouse); Expression system: E.coli; Expression region: 57-235aa; Sequence information: Extracellular Domain; Tag: N-terminal 6xHis-SUMO-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
• Additional_information
  MW: 35.7 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
• Storage_and_shipping
  Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
• Notes
  For research use only.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Gene
  Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.

• Gene target
  Tumor   necrosis   factor   Tnf  
• Gene symbol
  TNF, TNFSF13, RELT
• Short name
  Mouse Tumor necrosis factor (Tnf)
• Technique
  Mouse, mouses
• Host
  mouse
• Species
  Mouse, Mouses
• Alternative name
  Mouse Tumor necrosis factor (tumor necrosis factor)
• Alternative technique
  murine
• Alternative to gene target
  tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
• Tissue
  tumor

Gene info

• Identity
  HGNC:11892
• Gene
  TNF
• Long gene name
  tumor necrosis factor
• Synonyms gene
  • TNFA
• Synonyms gene name
  • tumor necrosis factor (TNF superfamily, member 2)
• Synonyms
  • TNFSF2
  • DIF
  • TNF-alpha
• Synonyms name
  • TNF superfamily, member 2
• GenBank acession
  • X02910
• Locus
  6p21.33
• Discovery year
  1986-01-01
• Entrez gene record
  7124
• Pubmed identfication
  • 2413547
  • 6392892
• Classification
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000031194

Gene info

• Identity
  HGNC:11928
• Gene
  TNFSF13
• Long gene name
  TNF superfamily member 13
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 13
• Synonyms
  • APRIL
  • CD256
• GenBank acession
  • AF046888
• Locus
  17p13.1
• Discovery year
  1998-12-04
• Entrez gene record
  8741
• Pubmed identfication
  • 9743536
• RefSeq identity
  • NM_003808
• Classification
  • Tumor necrosis factor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000108145

Gene info

• Identity
  HGNC:13764
• Gene
  RELT
• Long gene name
  RELT TNF receptor
• Synonyms gene
  • TNFRSF19L
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 19-like
  • RELT tumor necrosis factor receptor
• Synonyms
  • FLJ14993
• Synonyms name
  • receptor expressed in lymphoid tissues
• GenBank acession
  • AF319553
• Locus
  11q13.4
• Discovery year
  2002-02-08
• Entrez gene record
  84957
• Pubmed identfication
  • 11313261
  • 16547002
  • 16950202
  • 16389068
• RefSeq identity
  • NM_032871
• Classification
  • RELT family
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000167973

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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