Human Lys-63-specific deubiquitinase BRCC36 (BRCC3)

Description

Recombinant Human Lys-63-specific deubiquitinase BRCC36(BRCC3) expressed in E.coli
Specifications

Uniprot ID: P46736; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 2-316aa; Sequence information: Full Length of Mature Protein; Tag: N-terminal 6xHis-GST-tagged ; Purity: Greater than 90% as determined by SDS-PAGE.
Additional_information

MW: 65.9 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
Storage_and_shipping

Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
Notes

For research use only.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Gene target

Lys-63-specific deubiquitinase BRCC36 BRCC3
Gene symbol

BRCC3, IGLVI-63, IGHV3-63, CKAP4, DEPDC1B, RNU6-63P, GTF3C5, RGPD5, MECR
Short name

Lys-63-specific deubiquitinase BRCC36 (BRCC3)
Species

Human, Humans
Alternative name

H. sapiens L-lysine-63-specific deubiquitinase BRCC36 (BRCC3)

Identity

HGNC:24185
Gene

BRCC3
Long gene name

BRCA1/BRCA2-containing complex subunit 3
Synonyms gene
- CXorf53
Synonyms gene name
- chromosome X open reading frame 53
- BRCA1/BRCA2-containing complex, subunit 3
Synonyms
- C6.1A
- BRCC36
Synonyms name
- Lys-63-specific deubiquitinase
GenBank acession
- X64643
Locus

Xq28
Discovery year

2004-12-03
Entrez gene record

79184
Pubmed identfication
- 1303175
- 14636569
RefSeq identity
- NM_024332
Classification
- BRISC complex
- JAMM/MPN+ metallopeptidase family
- BRCA1 A complex
VEGA ID

OTTHUMG00000022658

Identity

HGNC:5938
Gene

IGLVI-63
Long gene name

immunoglobulin lambda variable (I)-63 (pseudogene)
Synonyms gene name
- immunoglobulin lambda variable (I)-63
- immunoglobulin lambda variable (I)-63 pseudogene
Synonyms
- IGLV(I)-63
GenBank acession
- D87022
Locus

22q11.22
Discovery year

2000-05-08
Entrez gene record

28765
RefSeq identity
- NG_000002
Classification
- Immunoglobulin lambda locus at 22q11.2
VEGA ID

OTTHUMG00000150855

Identity

HGNC:5616
Gene

IGHV3-63
Long gene name

immunoglobulin heavy variable 3-63 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable 3-63
- immunoglobulin heavy variable 3-63 pseudogene
GenBank acession
- M99681
Locus

14q32.33
Discovery year

2000-04-04
Entrez gene record

28415
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000151977

Identity

HGNC:4668
Gene

GTF3C5
Long gene name

general transcription factor IIIC subunit 5
Synonyms gene name
- general transcription factor IIIC, polypeptide 5 (63kD)
- general transcription factor IIIC, polypeptide 5, 63kDa
Synonyms
Synonyms name
- transcription factor IIIC, 63 kD
GenBank acession
- AF133124
Locus

9q34.13
Discovery year

1999-03-16
Entrez gene record

9328
Pubmed identfication
- 10373544
RefSeq identity
- NM_001122823
Classification
- General transcription factor IIIC complex subunits
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000020856

Identity

HGNC:19691
Gene

MECR
Long gene name

mitochondrial trans-2-enoyl-CoA reductase
Synonyms
- CGI-63
- NRBF1
- FASN2B
- ETR1
Synonyms name
- nuclear receptor binding factor 1
- mitochondrial 2-enoyl thioester reductase
Locus

1p35.3
Discovery year

2005-05-24
Entrez gene record

51102
Pubmed identfication
- 9795230
- 12654921
RefSeq identity
- NM_016011
VEGA ID

OTTHUMG00000059082