Human Inhibitor of nuclear factor kappa-B kinase subunit beta (IKBKB)
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Catalog numberCSB-EP011572HU-1MG
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PricePlease ask
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Size1MG
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DescriptionRecombinant Human Inhibitor of nuclear factor kappa-B kinase subunit beta(IKBKB) expressed in E.coli
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SpecificationsUniprot ID: O14920; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 1-756aa; Sequence information: Full Length; Tag: N-terminal 6xHis-tagged; Purity: Greater than 85% as determined by SDS-PAGE.
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Additional_informationMW: 92.5 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
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Storage_and_shippingShipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
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NotesFor research use only.
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Additional descriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Gene symbolIKBKB, IKBKB-DT
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Short nameInhibitor of factor kappa-B kinase subunit beta (IKBKB)
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SpeciesHuman, Humans
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Alternative nameH. sapiens suppressor on nuclear factor kappa-B phosphorylation catalyst functionnal sequence b (inhibitor on kappa light polypeptide gene enhancer in B-cells, kinase b)
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Alternative to gene targetinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, IKK-beta and IKK2 and IKKB and IMD15 and NFKBIKB, IKBKB and IDBG-19987 and ENSG00000104365 and 3551, transferase activity, nuclei, Ikbkb and IDBG-141021 and ENSMUSG00000031537 and 16150, IKBKB and IDBG-629838 and ENSBTAG00000007599 and 281854
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Gene info
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Identity
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Gene
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Long gene nameinhibitor of nuclear factor kappa B kinase subunit beta
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Synonyms gene name
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-02-11
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Entrez gene record
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Pubmed identfication
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Classification
- I kappa B kinases
- IKK complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameIKBKB divergent transcript
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Synonyms
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Synonyms name
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Locus
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Discovery year2020-09-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Divergent transcripts
