Human IgG receptor FcRn large subunit p51 (FCGRT)
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Catalog number
CSB-EP008545HU-100ug
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Price
Please ask
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Size
100ug
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Description
Recombinant Human IgG receptor FcRn large subunit p51(FCGRT),partial expressed in E.coli
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Specifications
Uniprot ID: P55899; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 24-297aa; Sequence information: Extracellular Domain; Tag: N-terminal GST-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
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Additional_information
MW: 57.4 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
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Storage_and_shipping
Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
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Notes
For research use only.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures.
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Additional description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
FCGRT
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Short name
IgG receptor FcRn subunit p51 (FCGRT)
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Technique
IgG, IgGs
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Isotype
IgG, IgG
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Species
Human, Humans
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Alternative name
H. sapiens Immunoglobulin G receptor FcRn large functionnal sequence p51 (fragment c fragment on Immunoglobulin G, receptor, transporter, alpha)
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Alternative technique
immunoglobulins
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Alternative to gene target
Fc fragment of IgG, receptor, transporter, alpha, alpha-chain and FCRN, FCGRT and IDBG-63001 and ENSG00000104870 and 2217, beta-2-microglobulin binding, Plasma membranes, Fcgrt and IDBG-181534 and ENSMUSG00000003420 and 14132, FCGRT and IDBG-640575 and ENSBTAG00000013926 and 338062
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Gene info
Product images
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