Human DNA replication licensing factor MCM2 (MCM2)

• Catalog number
  CSB-EP013590HU-500ug
• Price
  Please ask
• Size
  500ug

• Description
  Recombinant Human DNA replication licensing factor MCM2(MCM2) expressed in E.coli
• Specifications
  Uniprot ID: P49736; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 2-904aa; Sequence information: Full Length of Mature Protein; Tag: N-terminal 6xHis-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
• Additional_information
  MW: 105.8 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
• Storage_and_shipping
  Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
• Notes
  For research use only.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Test
  Replication factor subunits and DNA replication proteins are found in DNA replication complexes like GINS, MCM,.. and replication initiators producing two identical replicas of DNA from one original DNA molecule. This process occurs in all living organisms and is the basis for biological inheritance. DNA is made up of a double helix of two strands, and each strand of the original DNA molecule gene serves as a template for the production of the complementary strand, a process referred to as semiconservative replication. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication of genes.

• Gene target
  DNA   licensing   factor   MCM2   MCM2  
• Gene symbol
  MCM7, MCM2, PRKDC, HLA-DOA
• Short name
  DNA licensing factor MCM2 (MCM2)
• Technique
  dna
• Species
  Human, Humans
• Alternative name
  H. sapiens Desoxyribonucleic acid replication licensing factor MCM2 (MCM2)

Gene info

• Identity
  HGNC:6950
• Gene
  MCM7
• Long gene name
  minichromosome maintenance complex component 7
• Synonyms gene
  • MCM2
• Synonyms gene name
  • minichromosome maintenance deficient (S. cerevisiae) 7
  • MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)
• Synonyms
  • CDC47
  • PPP1R104
• Synonyms name
  • protein phosphatase 1, regulatory subunit 104
• Locus
  7q22.1
• Discovery year
  1994-12-13
• Entrez gene record
  4176
• Pubmed identfication
  • 7842741
• Classification
  • MCM family
  • MicroRNA protein coding host genes
  • minichromosome maintenance 2-7 complex
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000154671

Gene info

• Identity
  HGNC:6944
• Gene
  MCM2
• Long gene name
  minichromosome maintenance complex component 2
• Synonyms gene
  • CCNL1
  • CDCL1
• Synonyms gene name
  • minichromosome maintenance deficient (S. cerevisiae) 2 (mitotin)
  • MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)
• Synonyms
  • D3S3194
  • KIAA0030
  • BM28
  • cdc19
  • DFNA70
• Synonyms name
  • mitotin
• GenBank acession
  • X67334
• Locus
  3q21.3
• Discovery year
  1993-09-30
• Entrez gene record
  4171
• Pubmed identfication
  • 1710453
  • 8258304
  • 26196677
• Classification
  • MCM family
  • minichromosome maintenance 2-7 complex
• VEGA ID
  OTTHUMG00000159637

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

Gene info

• Identity
  HGNC:4936
• Gene
  HLA-DOA
• Long gene name
  major histocompatibility complex, class II, DO alpha
• Synonyms gene
  • HLA-DZA
  • HLA-DNA
• Synonyms
  • HLA-D0-alpha
• GenBank acession
  • M31525
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3111
• Pubmed identfication
  • 2370084
• RefSeq identity
  • NM_002119
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031211
• Locus Specific Databases
  • IMGT/HLA Database

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