Human DNA replication complex GINS protein PSF2 (GINS2)

• Catalog number
  CSB-EP896481HU-10ug
• Price
  Please ask
• Size
  10ug

• Description
  Recombinant Human DNA replication complex GINS protein PSF2(GINS2) expressed in E.coli
• Specifications
  Uniprot ID: Q9Y248; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 1-185aa; Sequence information: Full Length; Tag: N-terminal 6xHis-SUMO-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
• Additional_information
  MW: 37.4 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
• Storage_and_shipping
  Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
• Notes
  For research use only.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Test
  Replication factor subunits and DNA replication proteins are found in DNA replication complexes like GINS, MCM,.. and replication initiators producing two identical replicas of DNA from one original DNA molecule. This process occurs in all living organisms and is the basis for biological inheritance. DNA is made up of a double helix of two strands, and each strand of the original DNA molecule gene serves as a template for the production of the complementary strand, a process referred to as semiconservative replication. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication of genes.

• Gene target
  DNA   complex   GINS   protein   PSF2   GINS2  
• Gene symbol
  GINS2, PRKDC, TAP2, HLA-DOA
• Short name
  DNA complex GINS protein PSF2 (GINS2)
• Technique
  dna
• Species
  Human, Humans
• Alternative name
  H. sapiens Desoxyribonucleic acid replication aggregate GINS protein PSF2 (GINS2)

Gene info

• Identity
  HGNC:24575
• Gene
  GINS2
• Long gene name
  GINS complex subunit 2
• Synonyms gene name
  • GINS complex subunit 2 (Psf2 homolog)
• Synonyms
  • PSF2
  • Pfs2
• GenBank acession
  • BC003186
• Locus
  16q24.1
• Discovery year
  2006-05-04
• Entrez gene record
  51659
• Pubmed identfication
  • 11042152
  • 10810093
• RefSeq identity
  • NM_016095
• Classification
  • GINS complex
• VEGA ID
  OTTHUMG00000137646

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

Gene info

• Identity
  HGNC:44
• Gene
  TAP2
• Long gene name
  transporter 2, ATP binding cassette subfamily B member
• Synonyms gene
  • ABCB3
• Synonyms gene name
  • transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
• Synonyms
  • PSF2
  • RING11
  • D6S217E
• GenBank acession
  • M74447
• Locus
  6p21.32
• Discovery year
  1992-06-25
• Entrez gene record
  6891
• Pubmed identfication
  • 1529427
  • 1946428
  • 16395595
• RefSeq identity
  • NM_000544
• Classification
  • ATP binding cassette subfamily B
• VEGA ID
  OTTHUMG00000031068
• Locus Specific Databases
  • TAP2base: Mutation registry for TAP2 deficiency
  • IMGT/HLA Database
  • LRG_167

Gene info

• Identity
  HGNC:4936
• Gene
  HLA-DOA
• Long gene name
  major histocompatibility complex, class II, DO alpha
• Synonyms gene
  • HLA-DZA
  • HLA-DNA
• Synonyms
  • HLA-D0-alpha
• GenBank acession
  • M31525
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3111
• Pubmed identfication
  • 2370084
• RefSeq identity
  • NM_002119
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031211
• Locus Specific Databases
  • IMGT/HLA Database

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