Human DNA repair protein XRCC4 (XRCC4)

Description

Recombinant Human DNA repair protein XRCC4(XRCC4) expressed in E.coli
Specifications

Uniprot ID: Q13426; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 1-336aa; Sequence information: Full Length ; Tag: N-terminal GST-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
Additional_information

MW: 65.3 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
Storage_and_shipping

Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
Notes

For research use only.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Gene target

DNA repair protein XRCC4 XRCC4
Gene symbol

XRCC4, PRKDC, HLA-DOA
Short name

DNA repair protein XRCC4 (XRCC4)
Technique

dna
Species

Human, Humans
Alternative name

H. sapiens Desoxyribonucleic acid repair protein X-ray repair complementing defective repair in Chinese hamster cells 4 (X-ray repair complementing defective repair in Chinese hamster cells 4)
Alternative to gene target

X-ray repair complementing defective repair in Chinese hamster cells 4, XRCC4 and IDBG-32219 and ENSG00000152422 and 7518, protein C-terminus binding, nuclei, Xrcc4 and IDBG-171005 and ENSMUSG00000021615 and 108138, XRCC4 and IDBG-646520 and ENSBTAG00000024275 and 613590

Identity

HGNC:12831
Gene

XRCC4
Long gene name

X-ray repair cross complementing 4
Synonyms gene name
- X-ray repair complementing defective repair in Chinese hamster cells 4
Synonyms name
- X-ray repair, complementing defective, repair in Chinese hamster
- DNA repair protein XRCC4
GenBank acession
- AB017445
Locus

5q14.2
Discovery year

1990-10-16
Entrez gene record

7518
Pubmed identfication
- 1697445
- 7665175
RefSeq identity
- NM_022550
VEGA ID

OTTHUMG00000131319

Name

Targeted Gene Repair
Concept

Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
Tree numbers
- E02.095.301.500
- E05.393.420.301.500
- E05.393.420.601.575.500
Qualifiers

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