TRAF Family Member Associated NFKB Activator (TANK) Polyclonal Antibody (Human, Pig), Biotinylated

• Catalog number
  PAJ823Hu01-100ul-Biotin
• Price
  Please ask
• Size
  100ul

• Description
  A Rabbit polyclonal antibody against Human, Pig TRAF Family Member Associated NFKB Activator (TANK). This antibody is labeled with Biotin.
• Specifications
  Host: Rabbit; Species Reactivity: Human, Pig; Clonality: polyclonal; Tested applications: WB, IHC; Concentration: 500ug/ml; Isotype: IgG; Conjugation: Biotin
• Additional_information
  Sequence of the immunogen: TANK (Leu131~Ile369); Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Storage_and_shipping
  Upon receipt, store at -20°C or -80°C. Prepare working aliqotes prior to storage to avoid repeated freeze-thaw cycles.
• Notes
  Research Use Only.
• Properties
  If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Gene
  NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
• About
  Pigs and the smaller guinea pigs are frequent used as models for humans. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• Group
  Polyclonals and antibodies
• French translation
  anticorps

• Gene target
  TRAF   Family   Member   Associated   NFKB   Activator   TANK   Biotinylated  
• Gene symbol
  TANK, TANK-AS1, NFKB1
• Short name
  TRAF Family Member Associated NFKB Activator (TANK) Polyclonal Antibody ( , ), Biotinylated
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Species
  Pig, Humans, Pigs and Guinea pigs
• Alternative name
  TRAF family Member Associated NFKB Activator (TANK) polyclonal (antibody to-) (H. sapiens, swine), Biotinylated
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:11562
• Gene
  TANK
• Long gene name
  TRAF family member associated NFKB activator
• Synonyms gene
  • TRAF2
• Synonyms gene name
  • TRAF family member-associated NFKB activator
• Synonyms
  • I-TRAF
• GenBank acession
  • U59863
• Locus
  2q24.2
• Discovery year
  1997-06-12
• Entrez gene record
  10010
• Pubmed identfication
  • 8710854
  • 8855313
• RefSeq identity
  • NM_133484
• VEGA ID
  OTTHUMG00000132037

Gene info

• Identity
  HGNC:40575
• Gene
  TANK-AS1
• Long gene name
  TANK antisense RNA 1
• Locus
  2q24.2
• Discovery year
  2020-03-27
• Entrez gene record
  105373719
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:7794
• Gene
  NFKB1
• Long gene name
  nuclear factor kappa B subunit 1
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Synonyms
  • KBF1
  • p105
  • NFKB-p50
  • p50
  • NF-kappaB
  • NFkappaB
  • NF-kB1
• Synonyms name
  • Nuclear factor NF-kappa-B p105 subunit
• GenBank acession
  • M58603
• Locus
  4q24
• Discovery year
  1991-11-14
• Entrez gene record
  4790
• Pubmed identfication
  • 1992489
• RefSeq identity
  • NM_003998
• Classification
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
  • IPT domain containing
• VEGA ID
  OTTHUMG00000161080
• Locus Specific Databases
  • LRG_1316

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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