Stem Cell Factor Receptor (SCFR) Monoclonal Antibody (Rat), Biotinylated

• Catalog number
  MAA121Ra21-10ml-Biotin
• Price
  Please ask
• Size
  10ml

• Description
  A Mouse monoclonal antibody against Rat Stem Cell Factor Receptor (SCFR). This antibody is labeled with Biotin.
• Specifications
  Host: Mouse; Species Reactivity: Rat; Clonality: monoclonal; Tested applications: WB, IHC; Concentration: 1mg/mL; Isotype: IgG2b Kappa; Conjugation: Biotin
• Additional_information
  Sequence of the immunogen: Inquire for antigen sequence.; Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
• Storage_and_shipping
  Upon receipt, store at -20°C or -80°C. Prepare working aliqotes prior to storage to avoid repeated freeze-thaw cycles.
• Notes
  Research Use Only.
• Properties
  If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Additional description
  For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• Test
  Stem cell factors and stem cell growth factors will produce stem cells or be part of a transdifferentiation process to produce other cells. A cell can transdifferentiate by going back to the naive stem cell stadium or directly into the other cell, helped by the stem cell and transdifferentiationf actors. Stem cell growth factors or stem cell factors are mostly used to produce iPSCs or induced pluripotent stem cells by Jamaka or Thomson factors by using for example 5 Lenti-III-CMV viruses, expressing the Yamanaka iPSC factor set (Oct4, Sox2, Nanog and Lin28) + GFP positive control. Trans differentiation will omit the stem cell stadium but stem cell factors sill play an important role in trans differentiation strategies.
• French translation
  anticorps

• Gene target
  Stem   Factor   Receptor   SCFR   Monoclonal   Biotinylated  
• Gene symbol
  KIT
• Short name
  Stem Factor Receptor (SCFR) Monoclonal Antibody ( ), Biotinylated
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Rat
• Species
  Rat, Rats
• Alternative name
  progenitor cellular Factor Receptor (SCFR) monoclonal (antibody to-) (Rat), Biotinylated
• Alternative technique
  antibodies
• Tissue
  cell, stem

Gene info

• Identity
  HGNC:6342
• Gene
  KIT
• Long gene name
  KIT proto-oncogene, receptor tyrosine kinase
• Synonyms gene
  • PBT
• Synonyms gene name
  • piebald trait
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
• Synonyms
  • CD117
  • SCFR
  • C-Kit
• Synonyms name
  • mast/stem cell growth factor receptor Kit
• GenBank acession
  • S67773
• Locus
  4q12
• Discovery year
  1986-01-01
• Entrez gene record
  3815
• Pubmed identfication
  • 9027509
• RefSeq identity
  • NM_000222
• Classification
  • Receptor tyrosine kinases
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000128713
• Locus Specific Databases
  • LRG_307

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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