Single Ig IL1 Related Receptor (SIGIRR) Polyclonal Antibody (Pig), FITC
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Catalog number
PAM229Hu01-200ul-FITC
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Price
Please ask
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Size
200ul
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Description
A Rabbit polyclonal antibody against Pig Single Ig IL1 Related Receptor (SIGIRR). This antibody is labeled with FITC.
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Specifications
Host: Rabbit; Species Reactivity: Pig; Clonality: polyclonal; Tested applications: WB, IHC; Concentration: 500ug/ml; Isotype: IgG; Conjugation: FITC
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Additional_information
Sequence of the immunogen: SIGIRR (Met1~His118); Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Storage_and_shipping
Upon receipt, store at -20°C or -80°C. Prepare working aliqotes prior to storage to avoid repeated freeze-thaw cycles.
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Notes
Research Use Only.
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Properties
If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Cloud Clone Corp Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Cloud Clone Corp FITC is highly sensitive to pH extremes.
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Conjugation
Anti-FITC Antibody
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About
Pigs and the smaller guinea pigs are frequent used as models for humans. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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Group
Polyclonals and antibodies
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Additional description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translation
anticorps
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Gene target
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Gene symbol
IL1A, SIGIRR, IL1B, IL36A, IL1F10, IL36B
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Short name
Single Ig IL1 Receptor (SIGIRR) Polyclonal Antibody ( ), FITC
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Technique
Polyclonal, Antibody, FITC, antibodies against human proteins, antibodies for, Fluorescein, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Label
FITC
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Species
Pig, Pigs and Guinea pigs
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Alternative name
Single Ig IL1 Related Receptor (single immunoglobulin and toll-interleukin 1 receptor (TIR) domain) polyclonal (antibody to-) (swine), fluorecein
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Alternative technique
polyclonals, antibodies, fluorescine
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Alternative to gene target
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, SIGIRR and IDBG-16551 and ENSG00000185187 and 59307, protein binding, Plasma membranes, Sigirr and IDBG-211977 and ENSMUSG00000025494 and 24058, SIGIRR and IDBG-645604 and ENSBTAG00000011149 and 531801
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Gene info
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Identity
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Gene
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Long gene name
interleukin 1 alpha
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
interleukin 1 beta
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Synonyms
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GenBank acession
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Locus
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Discovery year
1989-03-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 36 alpha
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 6 (epsilon)
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Synonyms
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GenBank acession
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Locus
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Discovery year
2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
interleukin 36 beta
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 8 (eta)
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Synonyms
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GenBank acession
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Locus
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Discovery year
2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
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Tree numbers
- E01.370.225.500.607.512.240
- E01.370.225.750.551.512.240
- E05.200.500.607.512.240
- E05.200.750.551.512.240
- E05.478.583.375
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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