Recombinant Transforming Growth Factor Beta Receptor I (TGFbR1)
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Catalog number
RPA397Hu01
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Price
Please ask
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Size
10ug
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Source
Prokaryotic expression
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Predicted Molecular Mass KD
31.1kDa
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Accurate Molecular Mass KD
33kDa
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Organism species
Homo sapiens (Human)
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Item Name
Transforming Growth Factor Beta Receptor I
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Alternative Names
ACVRLK4; AAT5; ALK5; SKR4; TGFR-1; Activin A Receptor Type II-Like Kinase 53kDa; Activin receptor-like kinase 5; Serine/threonine-protein kinase receptor R4
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Research Area
Tumor immunity;Infection immunity;
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Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
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Traits
Freeze-dried powder
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Isoelectric Point
7
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Purity
≥ 98%
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Protein length
Glu162~Ala403
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Tag
two N-terminal Tags, His-tag and T7-tag
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Expression System
Prokaryotic expression
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Application
Positive Control; Immunogen; SDS-PAGE; WB.
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
TGFBR1
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Short name
Recombinant Transforming Growth Factor Beta Receptor I (TGFbR1)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
E.coli
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Species
Homo sapiens (Human)
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Alternative name
Rec. Transforming Growth Factor b Receptor I (transforming growth factor, b receptor 1)
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Alternative technique
rec
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Alternative to gene target
transforming growth factor, beta receptor 1, AAT5 and ACVRLK4 and ALK-5 and ALK5 and ESS1 and LDS1 and LDS1A and LDS2A and MSSE and SKR4 and TGFR-1, TGFBR1 and IDBG-78488 and ENSG00000106799 and 7046, transforming growth factor beta receptor activity, Cell surfaces, Tgfbr1 and IDBG-146050 and ENSMUSG00000007613 and 21812, TGFBR1 and IDBG-634152 and ENSBTAG00000018035 and 282382
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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