Recombinant TRAF Family Member Associated NFKB Activator (TANK)

Source

Prokaryotic expression
Predicted Molecular Mass KD

30.3kDa
Accurate Molecular Mass KD

NA
Organism species

Homo sapiens (Human)
Item Name

TRAF Family Member Associated NFKB Activator
Alternative Names

TRAF2; I-TRAF; TRAF-interacting protein
Research Area

Immune molecule;
Buffer Formulation

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Traits

Freeze-dried powder
Purity

≥ 95%
Protein length

Leu131~Ile369
Tag

N-terminal His-Tag, T7 tag
Expression System

Prokaryotic expression
Application

Positive Control; Immunogen; SDS-PAGE; WB.
Manual link
Gene

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
Additional source

Recombinants or rec. proteins
Group

recombinants

Gene target

TRAF Family Member Associated NFKB Activator TANK
Gene symbol

TANK, TANK-AS1, NFKB1
Short name

Recombinant TRAF Family Member Associated NFKB Activator (TANK)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E.coli
Species

Homo sapiens (Human)
Alternative name

Rec. TRAF family Member Associated NFKB Activator (TANK)
Alternative technique

rec

Identity

HGNC:7794
Gene

NFKB1
Long gene name

nuclear factor kappa B subunit 1
Synonyms gene name
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Synonyms
- KBF1
- p105
- NFKB-p50
- p50
- NF-kappaB
- NFkappaB
- NF-kB1
Synonyms name
- Nuclear factor NF-kappa-B p105 subunit
GenBank acession
- M58603
Locus

4q24
Discovery year

1991-11-14
Entrez gene record

4790
Pubmed identfication
- 1992489
RefSeq identity
- NM_003998
Classification
- NF-kappa B complex subunits
- Ankyrin repeat domain containing
- IPT domain containing
VEGA ID

OTTHUMG00000161080
Locus Specific Databases
- LRG_1316

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data